Evidence map›Paper›PMID 35008963›Full record

ArticleInternational journal of molecular sciences2022

Lack of Charge Interaction in the Ion Binding Site Determines Anion Selectivity in the Sodium Bicarbonate Cotransporter NBCe1.

Soojung Lee, Jason Lin, Inyeong Choi

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Soojung LeeDepartment of Cell Biology, Emory University School of Medicine, Atlanta, GA 30322, USA.
Jason LinDepartment of Cell Biology, Emory University School of Medicine, Atlanta, GA 30322, USA.
Inyeong ChoiDepartment of Cell Biology, Emory University School of Medicine, Atlanta, GA 30322, USA.

Funding

Structure/function analysis of the na/bicarbonate cotransportersR01GM078502 · NIGMS · EMORY UNIVERSITY · PI CHOI, INYEONG · 2007 to 2011
$1.6M
Testing a new strategy to reduce alcohol consumption by pHR21AA028606 · NIAAA · EMORY UNIVERSITY · PI CHOI, INYEONG · 2021 to 2022
$410k
Emory University URC_ChoiNational Institute of Health AA028606National Institute of Health GM078502NIAAA NIH HHS R21 AA028606NIGMS NIH HHS R01 GM078502
6 · The paper itself

Abstract

The Na/HCO

Indexed as

Binding SitesBicarbonatesBiological TransportHumansIon Channel GatingIonsMembrane PotentialsModels, MolecularMutationProtein BindingProtein DomainsProtein Interaction Domains and MotifsRecombinant Fusion ProteinsSodiumSodium-Bicarbonate SymportersStructure-Activity RelationshipBicarbonatesIonsRecombinant Fusion ProteinsSLC4A4 protein, humanSodiumSodium-Bicarbonate Symportersanion selectivityion transportNBCe1SLC4Asodium bicarbonate transporterstructure function

Identifiers

PMID35008963
PMCPMC8745181

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.