Evidence map›Paper›PMID 35008959›Full record

ArticleInternational journal of molecular sciences2022

Bisdemethoxycurcumin Induces Cell Apoptosis and Inhibits Human Brain Glioblastoma GBM 8401/

Te-Chun Hsia, Shu-Fen Peng, Fu-Shin Chueh, Kung-Wen Lu, Jiun-Long Yang, An-Cheng Huang, Fei-Ting Hsu, Rick Sai-Chuen Wu

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.7field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 10 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Te-Chun HsiaDepartment of Respiratory Therapy, China Medical University, Taichung 406, Taiwan.
Shu-Fen PengDepartment of Medical Research, China Medical University Hospital, Taichung 404, Taiwan.
Fu-Shin ChuehDepartment of Food Nutrition and Health Biotechnology, Asia University, Taichung 413, Taiwan.
Kung-Wen LuSchool of Post-Baccalaureate Chinese Medicine, College of Chinese Medicine, China Medical University, Taichung 406, Taiwan.
Jiun-Long YangDepartment of Nursing, St. Mary's Junior College of Medicine, Nursing and Management, Yilan 266, Taiwan.
An-Cheng HuangDepartment of Nursing, St. Mary's Junior College of Medicine, Nursing and Management, Yilan 266, Taiwan.ORCID 0000-0002-2278-2539
Fei-Ting HsuDepartment of Biological Science and Technology, China Medical University, Taichung 406, Taiwan.
Rick Sai-Chuen WuDepartment of Anesthesiology, China Medical University Hospital, Taichung 404, Taiwan.
China Medical University · TWMackay Junior College of Medicine, Nursing and Management · TWAsia University · TW

Funding

Ministry of Science and Technology, Taipei, Taiwan MOST 109-2314-B-039 -021-MY3
6 · The paper itself

Abstract

Bisdemethoxycurcumin (BDMC) has biological activities, including anticancer effects in vitro; however, its anticancer effects in human glioblastoma (GBM) cells have not been examined yet. This study aimed to evaluate the tumor inhibitory effect and molecular mechanism of BDMC on human GBM 8401/

Indexed as

AnimalsAntineoplastic Agents, PhytogenicApoptosisApoptosis Regulatory ProteinsBiobehavioral SciencesBiomarkersCell Line, TumorCell ProliferationCell SurvivalDiarylheptanoidsDisease Models, AnimalGene Expression RegulationGlioblastomaHumansMiceMice, NudeAntineoplastic Agents, PhytogenicApoptosis Regulatory ProteinsBiomarkersbisdemethoxycurcuminDiarylheptanoidsapoptosisBAXBcl-2BDMCglioblastoma (GBM) 8401/luc2 cellsxenograft

Identifiers

PMID35008959
PMCPMC8745075
OpenAlexW4205380462

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.