Evidence map›Paper›PMID 35008835›Full record

ArticleInternational journal of molecular sciences2021

Curcumin as an Epigenetic Therapeutic Agent in Myelodysplastic Syndromes (MDS).

Xiaoqing Xie, Daria Frank, Pradeep Kumar Patnana, Judith Schütte, Yahya Al-Matary, Longlong Liu, Lanying Wei, Martin Dugas, Julian Varghese, Subbaiah Chary Nimmagadda and 1 more

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.4field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 11 citations in OpenAlex.

  1. Regulation of grain protein content by the amino acid permease gene OsAAP4 in rice.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Xiaoqing XieDepartment of Medicine A, Hematology, Oncology and Pneumology, University Hospital Münster, 48149 Münster, Germany.
Daria FrankDepartment of Medicine A, Hematology, Oncology and Pneumology, University Hospital Münster, 48149 Münster, Germany.
Pradeep Kumar PatnanaDepartment of Medicine A, Hematology, Oncology and Pneumology, University Hospital Münster, 48149 Münster, Germany.
Judith SchütteDepartment of Medicine A, Hematology, Oncology and Pneumology, University Hospital Münster, 48149 Münster, Germany.
Yahya Al-MataryDepartment of Dermatology, University Hospital Essen, 45147 Essen, Germany.
Longlong LiuDepartment of Medicine A, Hematology, Oncology and Pneumology, University Hospital Münster, 48149 Münster, Germany.
Lanying WeiDepartment of Medicine A, Hematology, Oncology and Pneumology, University Hospital Münster, 48149 Münster, Germany.
Martin DugasInstitute of Medical Informatics, Heidelberg University Hospital, 69117 Heidelberg, Germany.
Julian VargheseInstitute of Medical Informatics, University Münster, 48149 Münster, Germany.
Subbaiah Chary NimmagaddaDepartment of Medicine A, Hematology, Oncology and Pneumology, University Hospital Münster, 48149 Münster, Germany.
Cyrus KhandanpourDepartment of Medicine A, Hematology, Oncology and Pneumology, University Hospital Münster, 48149 Münster, Germany.ORCID 0000-0003-4655-6269
University Hospital Münster · DEEssen University Hospital · DEHeidelberg University · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Growth Factor Independence 1 (GFI1) is a transcription factor with an important role in the regulation of development of myeloid and lymphoid cell lineages and was implicated in the development of myelodysplastic syndrome (MDS) and acute myeloid leukaemia (AML). Reduced expression of

Indexed as

Epigenesis, GeneticAnimalsCurcuminDisease-Free SurvivalDNA-Binding ProteinsGene Expression Regulation, LeukemicHemeLeukemia, Myeloid, AcuteMiceMice, TransgenicMyelodysplastic SyndromesPromoter Regions, GeneticTranscription FactorsCurcuminDNA-Binding ProteinsGfi1 protein, mouseHemeTranscription Factorsacute myeloid leukaemiacurcuminGFI1histone acetyltransferase inhibitor

Identifiers

PMID35008835
PMCPMC8745143
OpenAlexW4206562822

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.