Evidence map›Paper›PMID 35008828›Full record

ArticleInternational journal of molecular sciences2021

Acetylsalicylic Acid Reduces Passive Aortic Wall Stiffness and Cardiovascular Remodelling in a Mouse Model of Advanced Atherosclerosis.

Lynn Roth, Miche Rombouts, Dorien M Schrijvers, Besa Emini Veseli, Wim Martinet, Guido R Y De Meyer

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
0.5field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 8 citations in OpenAlex.

  1. Tacrolimus-associated neurotoxicity isolated to the brainstem: two illustrative cases and a systematic review of the literature.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2024
    Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Lynn RothLaboratory of Physiopharmacology, University of Antwerp, 2610 Antwerp, Belgium.ORCID 0000-0003-1397-1810
Miche RomboutsLaboratory of Physiopharmacology, University of Antwerp, 2610 Antwerp, Belgium.
Dorien M SchrijversLaboratory of Physiopharmacology, University of Antwerp, 2610 Antwerp, Belgium.
Besa Emini VeseliLaboratory of Physiopharmacology, University of Antwerp, 2610 Antwerp, Belgium.
Wim MartinetLaboratory of Physiopharmacology, University of Antwerp, 2610 Antwerp, Belgium.ORCID 0000-0003-1967-9343
Guido R Y De MeyerLaboratory of Physiopharmacology, University of Antwerp, 2610 Antwerp, Belgium.ORCID 0000-0003-3848-8702
University of Antwerp · BE

Funding

Horizon 2020 675527Universiteit Antwerpen 33931Universiteit Antwerpen 40183
6 · The paper itself

Abstract

Acetylsalicylic acid (ASA) is widely used in secondary prevention of cardiovascular (CV) disease, mainly because of its antithrombotic effects. Here, we investigated whether ASA can prevent the progression of vessel wall remodelling, atherosclerosis, and CV complications in apolipoprotein E deficient (

Indexed as

Vascular RemodelingVascular StiffnessAnimalsAortaApolipoproteins EAspirinAtherosclerosisBlood PressureDisease Models, AnimalDisease ProgressionFemaleFibrillin-1Kaplan-Meier EstimateLymphocytesMiceMyocardial InfarctionApolipoproteins EAspirinFibrillin-1arterial stiffnessaspirincollagenelastinneutrophil–lymphocyte ratioSMAD

Identifiers

PMID35008828
PMCPMC8745264
OpenAlexW4206239318

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.