Evidence map›Paper›PMID 35008805›Full record

ArticleInternational journal of molecular sciences2021

Novel Tetrazole-Based Antimicrobial Agents Targeting Clinical Bacteria Strains: Exploring the Inhibition of

Piotr Roszkowski, Jolanta Szymańska-Majchrzak, Michał Koliński, Sebastian Kmiecik, Małgorzata Wrzosek, Marta Struga, Daniel Szulczyk

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 18 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Antibacterial Activity and Mechanism ofInternational journal of molecular sciences · 2024
    Article
  7. Synthesis of tetrazole hybridized with thiazole, thiophene or thiadiazole derivatives, molecular modelling and antimicrobial activity.Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society · 2024
    Article
  8. Recent Development of DNA Gyrase Inhibitors: An Update.Mini reviews in medicinal chemistry · 2024
    Review
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Piotr RoszkowskiFaculty of Chemistry, University of Warsaw, Pasteura 1, 02-093 Warszawa, Poland.ORCID 0000-0001-9793-5248
Jolanta Szymańska-MajchrzakChair and Department of Biochemistry, Medical University of Warsaw, 02-097 Warszawa, Poland.ORCID 0000-0001-7607-7643
Michał KolińskiBioinformatics Laboratory, Mossakowski Medical Research Institute, Polish Academy of Sciences, 5 Pawinskiego St., 02-106 Warsaw, Poland.ORCID 0000-0003-1047-2186
Sebastian KmiecikBiological and Chemical Research Centre, Faculty of Chemistry, University of Warsaw, 02-089 Warsaw, Poland.ORCID 0000-0001-7623-0935
Małgorzata WrzosekDepartment of Biochemistry and Pharmacogenomics, Faculty of Pharmacy, Medical University of Warsaw, 02-097 Warsaw, Poland.ORCID 0000-0002-9820-3871
Marta StrugaChair and Department of Biochemistry, Medical University of Warsaw, 02-097 Warszawa, Poland.ORCID 0000-0002-0181-3607
Daniel SzulczykChair and Department of Biochemistry, Medical University of Warsaw, 02-097 Warszawa, Poland.ORCID 0000-0003-3083-456X
Medical University of Warsaw · PLUniversity of Warsaw · PLMossakowski Medical Research Institute, Polish Academy of Sciences · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Eleven novel imide-tetrazoles were synthesized. In the initial stage of research, in silico structure-based pharmacological prediction was conducted. All compounds were screened for antimicrobial activity using standard and clinical strains. Within the studied group, compounds

Indexed as

Anti-Bacterial AgentsDNA GyraseDNA Topoisomerase IVMicrobial Sensitivity TestsMolecular Docking SimulationProton Magnetic Resonance SpectroscopyStaphylococcus aureusTetrazolesTopoisomerase II InhibitorsAnti-Bacterial AgentsDNA GyraseDNA Topoisomerase IVTetrazolesTopoisomerase II Inhibitorsantibacterialantimicrobialgyrasetetrazoletopoisomerase

Identifiers

PMID35008805
PMCPMC8745314
OpenAlexW4200521057

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.