Evidence map›Paper›PMID 35008688›Full record

ArticleInternational journal of molecular sciences2021

Mapping and Characterization of HCMV-Specific Unconventional HLA-E-Restricted CD8 T Cell Populations and Associated NK and T Cell Responses Using HLA/Peptide Tetramers and Spectral Flow Cytometry.

Amélie Rousselière, Laurence Delbos, Céline Bressollette, Maïlys Berthaume, Béatrice Charreau

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.4field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Amélie RousselièreINSERM, Center for Research in Transplantation and Translational Immunology, Nantes Université, UMR 1064, CHU Nantes, F-44000 Nantes, France.
Laurence DelbosINSERM, Center for Research in Transplantation and Translational Immunology, Nantes Université, UMR 1064, CHU Nantes, F-44000 Nantes, France.
Céline BressolletteINSERM, Center for Research in Transplantation and Translational Immunology, Nantes Université, UMR 1064, CHU Nantes, F-44000 Nantes, France.ORCID 0000-0001-5175-0790
Maïlys BerthaumeINSERM, Center for Research in Transplantation and Translational Immunology, Nantes Université, UMR 1064, CHU Nantes, F-44000 Nantes, France.
Béatrice CharreauINSERM, Center for Research in Transplantation and Translational Immunology, Nantes Université, UMR 1064, CHU Nantes, F-44000 Nantes, France.ORCID 0000-0001-5870-4615
Inserm · FR

Funding

Association Grégory Lemarchal RF20190502487Insttitut de Recherche en santé respiratoire des Pays de la Loire LSC 10280Vaincre la Mucoviscidose RF20190502487
6 · The paper itself

Abstract

HCMV drives complex and multiple cellular immune responses, which causes a persistent immune imprint in hosts. This study aimed to achieve both a quantitative determination of the frequency for various anti-HCMV immune cell subsets, including CD8 T, γδT, NK cells, and a qualitative analysis of their phenotype. To map the various anti-HCMV cellular responses, we used a combination of three HLA

Indexed as

Flow CytometryCD8-Positive T-LymphocytesCell DifferentiationCytomegalovirusCytomegalovirus InfectionsHistocompatibility Antigens Class IHLA-E AntigensHumansImmunophenotypingKiller Cells, NaturalLymphocyte CountPeptidesReceptors, Antigen, T-Cell, alpha-betaHistocompatibility Antigens Class IHLA-E AntigensPeptidesReceptors, Antigen, T-Cell, alpha-betaCD8 T cellsHCMVHLA-ENKpHLA tetramersspectral flow cytometryγδT

Identifiers

PMID35008688
PMCPMC8745070
OpenAlexW4200498222

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.