Evidence map›Paper›PMID 35008556›Full record

ReviewInternational journal of molecular sciences2021

The Application of Nanoparticles in Diagnosis and Treatment of Kidney Diseases.

Patrycja Paluszkiewicz, Adrian Martuszewski, Natalia Zaręba, Kamila Wala, Mirosław Banasik, Marta Kepinska

Open access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 51 citations in OpenAlex.

  1. Review
  2. Article
  3. Application of nanoparticles in antibody drug delivery.Frontiers in bioengineering and biotechnology · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Patrycja PaluszkiewiczDepartment of Emergency Medical Service, Wroclaw Medical University, Bartla 5, 50-367 Wroclaw, Poland.ORCID 0000-0002-5701-9349
Adrian MartuszewskiDepartment of Population Health, Division of Environmental Health and Occupational Medicine, Wroclaw Medical University, Mikulicza-Radeckiego 7, 50-368 Wroclaw, Poland.ORCID 0000-0002-3620-6380
Natalia ZarębaDepartment of Pharmaceutical Biochemistry, Division of Biomedical and Environmental Analysis, Faculty of Pharmacy, Wroclaw Medical University, Borowska 211a, 50-556 Wrocław, Poland.
Kamila WalaFaculty of Medicine, Wroclaw Medical University, Pasteura 1, 50-367 Wroclaw, Poland.
Mirosław BanasikDepartment of Nephrology and Transplantation Medicine, Wroclaw Medical University, Borowska 213, 50-556 Wroclaw, Poland.ORCID 0000-0002-0588-1551
Marta KepinskaDepartment of Pharmaceutical Biochemistry, Division of Biomedical and Environmental Analysis, Faculty of Pharmacy, Wroclaw Medical University, Borowska 211a, 50-556 Wrocław, Poland.ORCID 0000-0002-0935-5663
Wroclaw Medical University · PL

Funding

Ministry of Education and Science in the "Regional Initiative of Excellence" programme 016/RID/2018/19
6 · The paper itself

Abstract

Nanomedicine is currently showing great promise for new methods of diagnosing and treating many diseases, particularly in kidney disease and transplantation. The unique properties of nanoparticles arise from the diversity of size effects, used to design targeted nanoparticles for specific cells or tissues, taking renal clearance and tubular secretion mechanisms into account. The design of surface particles on nanoparticles offers a wide range of possibilities, among which antibodies play an important role. Nanoparticles find applications in encapsulated drug delivery systems containing immunosuppressants and other drugs, in imaging, gene therapies and many other branches of medicine. They have the potential to revolutionize kidney transplantation by reducing and preventing ischemia-reperfusion injury, more efficiently delivering drugs to the graft site while avoiding systemic effects, accurately localizing and visualising the diseased site and enabling continuous monitoring of graft function. So far, there are known nanoparticles with no toxic effects on human tissue, although further studies are still needed to confirm their safety.

Indexed as

AnimalsHumansKidneyKidney DiseasesNanomedicineNanoparticlesReperfusion InjuryKTxnanomaterialnanomedicinenanostructuresnanotechnologyrenalSPIOtransplantation

Identifiers

PMID35008556
PMCPMC8745391
OpenAlexW4200069478

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.