Evidence map›Paper›PMID 35008421›Full record

ReviewCancers2022

Neuropsychiatric Disorders and Frailty in Older Adults over the Spectrum of Cancer: A Narrative Review.

Mariya Muzyka, Luca Tagliafico, Gianluca Serafini, Ilaria Baiardini, Fulvio Braido, Alessio Nencioni, Fiammetta Monacelli

Open access · goldAbstract readReview
In one paragraph

Review in Cancers, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.6field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Mariya MuzykaIRCCS Ospedale Policlinico San Martino, 16132 Genoa, Italy.
Luca TagliaficoIRCCS Ospedale Policlinico San Martino, 16132 Genoa, Italy.
Gianluca SerafiniIRCCS Ospedale Policlinico San Martino, 16132 Genoa, Italy.ORCID 0000-0002-6631-856X
Ilaria BaiardiniIRCCS Ospedale Policlinico San Martino, 16132 Genoa, Italy.ORCID 0000-0002-8244-9922
Fulvio BraidoIRCCS Ospedale Policlinico San Martino, 16132 Genoa, Italy.
Alessio NencioniIRCCS Ospedale Policlinico San Martino, 16132 Genoa, Italy.
Fiammetta MonacelliIRCCS Ospedale Policlinico San Martino, 16132 Genoa, Italy.
Ospedale Policlinico San Martino · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe interplay between different neuropsychiatric conditions, beyond dementia, in the presence of a diagnosis of cancer in older adults may mediate patients' fitness and cancer-related outcomes. Here, we aimed to investigate the presence of depression, sleep disturbances, anxiety, attitude, motivation, and support in older adults receiving a diagnosis of cancer and the dimension of frailty in order to understand the magnitude of the problem.

methodsThis review provides an update of the state of the art based on references from searches of PubMed between 2000 and June 2021.

resultsThe evidence obtained underscored the tight association between frailty and unfavorable clinical outcomes in older adults with cancer. Given the intrinsic correlation of neuropsychiatric disorders with frailty in the realm of cancer survivorship, the evidence showed they might have a correlation with unfavorable clinical outcomes, late-life geriatric syndromes and higher degree of frailty.

conclusionsThe identification of common vulnerabilities among neuropsychiatric disorders, frailty, and cancer may hold promise to unmask similar shared pathways, potentially intercepting targeted new interventions over the spectrum of cancer with the delivery of better pathways of care for older adults with cancer.

Indexed as

anxietyattitudecancerdepressionfrailtymotivationneuropsychiatryolder adultssleep disturbancessupport

Identifiers

PMID35008421
PMCPMC8796027
OpenAlexW4206093726

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.