Evidence map›Paper›PMID 35008309›Full record

ArticleCancers2021

Contemporary Treatment Patterns and Response in Relapsed/Refractory Cutaneous T-Cell Lymphoma (CTCL) across Five European Countries.

Chalid Assaf, Nathalie Waser, Martine Bagot, Mary He, Tina Li, Mehul Dalal, Francois Gavini, Fabrizio Trinchese, Athanasios Zomas, Meredith Little and 3 more

Open access · goldAbstract read
In one paragraph

Article in Cancers, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
2.7field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 15 citations in OpenAlex.

  1. Guideline
  2. Article
  3. Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 7 institutions in 7 countries.

Chalid AssafDepartment of Dermatology, HELIOS Klinikum Krefeld, Academic Teaching Hospital of the University of Aachen, 47805 Krefeld, Germany.
Nathalie WaserICON Plc, 450-688 West Hastings St., Vancouver, BC V6B 1P1, Canada.
Martine BagotDepartment of Dermatology, Hôpital Saint-Louis, 75010 Paris, France.
Mary HeICON Plc, 450-688 West Hastings St., Vancouver, BC V6B 1P1, Canada.
Tina LiICON Plc, 450-688 West Hastings St., Vancouver, BC V6B 1P1, Canada.
Mehul DalalTakeda Development Center Americas, Inc. (TDCA), Lexington, MA 02139, USA.
Francois GaviniTakeda Development Center Americas, Inc. (TDCA), Lexington, MA 02139, USA.
Fabrizio TrincheseTakeda Pharmaceuticals International AG, 8152 Zurich, Switzerland.ORCID 0000-0002-7667-0778
Athanasios ZomasTakeda Pharmaceuticals International AG, 8152 Zurich, Switzerland.
Meredith LittleTakeda Development Center Americas, Inc. (TDCA), Lexington, MA 02139, USA.
Nicola PimpinelliDepartment of Health Sciences, Dermatology Unit, University of Florence, 50121 Florence, Italy.
Pablo L Ortiz-RomeroInstitute I+12, Medical School, Hospital Universitario 12 de Octubre, University Complutense, 28040 Madrid, Spain.
Timothy M IllidgeManchester NIHR Biomedical Research Centre, Christie Hospital, University of Manchester, Manchester M20 4BX, UK.ORCID 0000-0003-3191-7324
Takeda (United States) · USTakeda (Switzerland) · CHHelios Klinikum Krefeld · DEHôpital Saint-Louis · FRHospital Universitario 12 De Octubre · ESUniversity of Florence · ITUniversity of Manchester · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The treatment pattern of cutaneous T-cell lymphoma (CTCL) remains diverse and patient-tailored. The objective of this study was to describe the treatment patterns and outcomes in CTCL patients who were refractory or had relapsed (R/R) after a systemic therapy. A retrospective chart review study was conducted at 27 sites in France, Germany, Italy, Spain and the United Kingdom (UK) of patients who received a first course of systemic therapy and relapsed or were refractory. Data were collected longitudinally from diagnosis to first-, second- and third-line therapy. The study included 157 patients, with a median follow-up of 3.2 years. In total, 151 proceeded to second-line and 90 to third-line therapy. In the first line (

Indexed as

CTCLobservational studyOSoutcomepcALCLtreatmentTTNT

Identifiers

PMID35008309
PMCPMC8750476
OpenAlexW4200351261

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.