ReviewCancers2021
Exercise and Childhood Cancer-A Historical Review.
Review in Cancers, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Exercise intervention for children with acute leukemia: a best evidence summary.Frontiers in pediatrics · 2026Pooled it
- Physical capacity in children and adolescents with newly diagnosed cancer: A systematic review and meta-analysis.Pediatric blood & cancer · 2024Pooled it
- Effect of exercise on bone health in children and adolescents with cancer during and after oncological treatment: A systematic review and meta-analysis.Frontiers in physiology · 2023Pooled it
- Sarcopenia in pediatric gastroenterology and hepatology: an updated review.Clinical and experimental pediatrics · 2026Article
- Development and Usability of the "FORTEe Get Strong" App to Promote Physical Activity and Health Awareness in Children and Adolescents With Cancer During Intensive Treatment Using an App-Based Approach: Mixed Methods Study.JMIR serious games · 2026Article
- Implementing exercise interventions in pediatric oncology: an expert consensus framework from the FORTEe project.Frontiers in oncology · 2026Article
- The use of an augmented reality app to support an exercise intervention for children and young people with cancer: perspectives of users and exercise and healthcare professionals in the FORTEe trial.Frontiers in pediatrics · 2026Article
- The multidimensional roles and mechanisms of exercise intervention in pediatric oncology.Frontiers in immunology · 2026Review
- Incidence, characteristics and suggestions for prevention of adverse events in supervised pediatric oncology exercise sessions.Frontiers in pediatrics · 2026Article
- Physical Activity and Childhood Cancer: Present Status and Future Directions.American journal of lifestyle medicine · 2025Article
- Implementing an online-delivered exercise program for childhood cancer survivors: A hybrid effectiveness-implementation protocol for the MERRIER study.JSAMS plus · 2025Article
- Parental influence on Chinese childhood cancer survivors' physical activity: a mixed methods study.Scientific reports · 2025Article
- The evolution of nutritional care in children and young people with acute lymphoblastic leukaemia: a narrative review.Journal of human nutrition and dietetics : the official journal of the British Dietetic Association · 2025Review
- Childhood cancer patients' experiences of a structured exercise program. A qualitative study using reflexive thematic analysis.Frontiers in pediatrics · 2025Article
- Distinct NK cell function and gene expression in children with acute lymphoblastic leukemia in remission before and after acute exercise: an exploratory study.Frontiers in immunology · 2025Article
- Aging and cancer.Molecular cancer · 2024Review
- Effects of Exercise and Physical Activity Levels on Childhood Cancer: An Umbrella Review.Healthcare (Basel, Switzerland) · 2023Review
- Safety, Feasibility and Efficacy of LokomatCancers · 2023Article
- Is an Exercise Program for Pediatric Cancer Patients in Palliative Care Feasible and Supportive?-A Case Series.Children (Basel, Switzerland) · 2023Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Childhood cancer survivors are at risk of developing important adverse effects, many of which persist for years after the end of treatment. The implementation of interventions aiming at attenuating tumor/treatment-associated adverse effects is therefore a major issue in pediatric oncology, and there is growing evidence that physical exercise could help in this regard. The present review aims to summarize the main milestones achieved in pediatric exercise oncology. For this purpose, we conducted a systematic review of relevant studies written in English in the electronic database PubMed (from inception to 14 August 2021). This review traces the field of pediatric exercise oncology throughout recent history based on three fundamental pillars: (i) exercise during childhood cancer treatment; (ii) exercise during/after hematopoietic stem cell transplantation; and (iii) exercise after childhood cancer treatment. Accumulating evidence--although still preliminary in many cases--supports the safety and potential benefits of regular exercise (with no major contraindications in general) in the childhood cancer continuum, even during the most aggressive phases of treatment. Exercise can indeed represent an effective coadjuvant therapy for attenuating cancer-related adverse effects.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.