Evidence map›Paper›PMID 35008207›Full record

ArticleCancers2021

Bcr-TMP, a Novel Nanomolar-Active Compound That Exhibits Both MYB- and Microtubule-Inhibitory Activity.

Maria V Yusenko, Abhiruchi Biyanee, Daria Frank, Leonhard H F Köhler, Mattias K Andersson, Cyrus Khandanpour, Rainer Schobert, Göran Stenman, Bernhard Biersack, Karl-Heinz Klempnauer

Open access · goldAbstract read
In one paragraph

Article in Cancers, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 13 citations in OpenAlex.

  1. Review
  2. Review
  3. Transcription Factor MYB as Therapeutic Target: Current Developments.International journal of molecular sciences · 2024
    Review
  4. Article
  5. Emerging role of MYB transcription factors in cancer drug resistance.Cancer drug resistance (Alhambra, Calif.) · 2024
    Review
  6. Article
  7. Review
  8. Article
  9. Synthetic oleanane triterpenoids suppressFrontiers in oncology · 2023
    Article
  10. A New Naphthopyran Derivative CombinesACS medicinal chemistry letters · 2022
    Article
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

Maria V YusenkoInstitute for Biochemistry, Westfälische-Wilhelms-Universität, 48149 Munster, Germany.
Abhiruchi BiyaneeInstitute for Biochemistry, Westfälische-Wilhelms-Universität, 48149 Munster, Germany.
Daria FrankDepartment of Medicine A, Hematology and Oncology, University Hospital, Westfälische-Wilhelms-Universität, 48149 Munster, Germany.
Leonhard H F KöhlerOrganic Chemistry Laboratory, Universität Bayreuth, 95440 Bayreuth, Germany.
Mattias K AnderssonSahlgrenska Center for Cancer Research, Department of Pathology, University of Gothenburg, 41345 Gothenburg, Sweden.ORCID 0000-0001-6391-2048
Cyrus KhandanpourDepartment of Medicine A, Hematology and Oncology, University Hospital, Westfälische-Wilhelms-Universität, 48149 Munster, Germany.ORCID 0000-0003-4655-6269
Rainer SchobertOrganic Chemistry Laboratory, Universität Bayreuth, 95440 Bayreuth, Germany.ORCID 0000-0002-8413-4342
Göran StenmanSahlgrenska Center for Cancer Research, Department of Pathology, University of Gothenburg, 41345 Gothenburg, Sweden.ORCID 0000-0003-1017-7363
Bernhard BiersackOrganic Chemistry Laboratory, Universität Bayreuth, 95440 Bayreuth, Germany.
Karl-Heinz KlempnauerInstitute for Biochemistry, Westfälische-Wilhelms-Universität, 48149 Munster, Germany.
University of Münster · DEUniversity of Bayreuth · DESahlgrenska University Hospital · SE

Funding

Wilhelm Sander Stiftung Projekt 2020.071.1
6 · The paper itself

Abstract

Studies of the role of MYB in human malignancies have highlighted MYB as a potential drug target for acute myeloid leukemia (AML) and adenoid cystic carcinoma (ACC). Here, we present the initial characterization of 2-amino-4-(3,4,5-trimethoxyphenyl)-4

Indexed as

acute myeloid leukemiaadenoid cystic carcinomainhibitormicrotubule disruptionMYB

Identifiers

PMID35008207
PMCPMC8750090
OpenAlexW4200330684

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.