Evidence map›Paper›PMID 35008196›Full record

ReviewCancers2021

Review of the Geant4-DNA Simulation Toolkit for Radiobiological Applications at the Cellular and DNA Level.

Ioanna Kyriakou, Dousatsu Sakata, Hoang Ngoc Tran, Yann Perrot, Wook-Geun Shin, Nathanael Lampe, Sara Zein, Marie Claude Bordage, Susanna Guatelli, Carmen Villagrasa and 2 more

Open access · goldAbstract readReview
In one paragraph

Review in Cancers, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed
11.3field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 112 citations in OpenAlex.

  1. Article
  2. Monte Carlo microdosimetry ofEJNMMI physics · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 7 institutions in 5 countries.

Ioanna KyriakouMedical Physics Laboratory, Department of Medicine, University of Ioannina, 45110 Ioannina, Greece.
Dousatsu SakataDepartment of Accelerator and Medical Physics, Institute of Quantum Medical Science, QST, Chiba 263-8555, Japan.ORCID 0000-0002-8398-3334
Hoang Ngoc TranBordeaux University, CNRS/IN2P3, CENBG, UMR 5797, 33170 Gradignan, France.ORCID 0000-0002-9243-6842
Yann PerrotLaboratoire de Dosimétrie des Rayonnements Ionisants, IRSN, Institut de Radioprotection et de Sûreté Nucléaire BP17, 92262 Fontenay-aux-Roses, France.ORCID 0000-0001-9043-5857
Wook-Geun ShinDepartment of Radiation Oncology, Seoul National University Hospital, Seoul 03080, Korea.ORCID 0000-0002-8622-1888
Nathanael LampeIndependent Researcher, Melbourne, VIC 3000, Australia.ORCID 0000-0002-0593-1766
Sara ZeinBordeaux University, CNRS/IN2P3, CENBG, UMR 5797, 33170 Gradignan, France.
Marie Claude BordageUniversite Toulouse III-Paul Sabatier, UMR 1037, CRCT, 31034 Toulouse, France.ORCID 0000-0003-4735-7325
Susanna GuatelliCentre for Medical Radiation Physics, University of Wollongong and Illawarra Health and Medical Research Institute, Wollongong, NSW 2522, Australia.
Carmen VillagrasaLaboratoire de Dosimétrie des Rayonnements Ionisants, IRSN, Institut de Radioprotection et de Sûreté Nucléaire BP17, 92262 Fontenay-aux-Roses, France.
Dimitris EmfietzoglouMedical Physics Laboratory, Department of Medicine, University of Ioannina, 45110 Ioannina, Greece.
Sébastien IncertiBordeaux University, CNRS/IN2P3, CENBG, UMR 5797, 33170 Gradignan, France.ORCID 0000-0002-0619-2053
Centre National de la Recherche Scientifique · FRInstitut de Radioprotection et de Sûreté Nucléaire · FRUniversity of Ioannina · GRNational Institutes for Quantum Science and Technology · JPSeoul National University Hospital · KRUniversité Toulouse III - Paul Sabatier · FRUniversity of Wollongong · AU

Funding

European Space Agency 4000126645/19/NL/BWEuropean Space Agency 4000132935/21/NL/CRS
6 · The paper itself

Abstract

The Geant4-DNA low energy extension of the Geant4 Monte Carlo (MC) toolkit is a continuously evolving MC simulation code permitting mechanistic studies of cellular radiobiological effects. Geant4-DNA considers the physical, chemical, and biological stages of the action of ionizing radiation (in the form of x- and γ-ray photons, electrons and β

Indexed as

DNA damageDNA repairGeant4-DNAIRTmechanistic modelingMonte Carloradiobiological modellingstep by steptrack-structure

Identifiers

PMID35008196
PMCPMC8749997
OpenAlexW4200190079

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.