Evidence map›Paper›PMID 35008181›Full record

ArticleCancers2021

Surgical Margins Status and Prognosis after Resection of Oral Cavity Squamous Cell Carcinoma: Results from a Taiwanese Nationwide Registry-Based Study.

Chung-Jan Kang, Yu-Wen Wen, Shu-Ru Lee, Li-Yu Lee, Chuen Hsueh, Chien-Yu Lin, Kang-Hsing Fan, Hung-Ming Wang, Chia-Hsun Hsieh, Shu-Hang Ng and 12 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cancers, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Review
  2. Article
  3. Repurposing niclosamide to mitigate inflammaging: a review of multi-target mechanisms in cellular senescence and age-related decline.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2026
    Review
  4. Article
  5. Pattern of Mandibular Bone Invasion as a Prognostic Factor.Diagnostics (Basel, Switzerland) · 2025
    Article
  6. Article
  7. Article
  8. Review
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors.

Chung-Jan KangDepartment of Otorhinolaryngology, Head and Neck Surgery, Chang Gung Memorial Hospital, Medical College of Chang Gung University, Taoyuan 333, Taiwan.ORCID 0000-0002-5333-9396
Yu-Wen WenClinical Informatics and Medical Statistics Research Center, Medical College of Chang Gung University, Taoyuan 333, Taiwan.ORCID 0000-0002-7979-3845
Shu-Ru LeeResearch Service Center for Health Information, Chang Gung University, Taoyuan 333, Taiwan.
Li-Yu LeeDepartment of Pathology, Chang Gung Memorial Hospital, Medical College of Chang Gung University, Taoyuan 333, Taiwan.
Chuen HsuehDepartment of Pathology, Chang Gung Memorial Hospital, Medical College of Chang Gung University, Taoyuan 333, Taiwan.
Chien-Yu LinDepartment of Radiation Oncology, Chang Gung Memorial Hospital, Medical College of Chang Gung University, Taoyuan 333, Taiwan.
Kang-Hsing FanDepartment of Radiation Oncology, Chang Gung Memorial Hospital, Medical College of Chang Gung University, Taoyuan 333, Taiwan.
Hung-Ming WangDepartment of Medical Oncology, Chang Gung Memorial Hospital, Medical College of Chang Gung University, Taoyuan 333, Taiwan.
Chia-Hsun HsiehDepartment of Medical Oncology, Chang Gung Memorial Hospital, Medical College of Chang Gung University, Taoyuan 333, Taiwan.
Shu-Hang NgDepartment of Diagnostic Radiology, Chang Gung Memorial Hospital, Medical College of Chang Gung University, Taoyuan 333, Taiwan.
Chih-Hua YehDepartment of Diagnostic Radiology, Chang Gung Memorial Hospital, Medical College of Chang Gung University, Taoyuan 333, Taiwan.
Chih-Hung LinDepartment of Plastic and Reconstructive Surgery, Chang Gung Memorial Hospital, Medical College of Chang Gung University, Taoyuan 333, Taiwan.
Chung-Kan TsaoDepartment of Plastic and Reconstructive Surgery, Chang Gung Memorial Hospital, Medical College of Chang Gung University, Taoyuan 333, Taiwan.
Tuan-Jen FangDepartment of Otorhinolaryngology, Head and Neck Surgery, Chang Gung Memorial Hospital, Medical College of Chang Gung University, Taoyuan 333, Taiwan.
Shiang-Fu HuangDepartment of Otorhinolaryngology, Head and Neck Surgery, Chang Gung Memorial Hospital, Medical College of Chang Gung University, Taoyuan 333, Taiwan.
Li-Ang LeeDepartment of Otorhinolaryngology, Head and Neck Surgery, Chang Gung Memorial Hospital, Medical College of Chang Gung University, Taoyuan 333, Taiwan.ORCID 0000-0001-8414-595X
Ku-Hao FangDepartment of Otorhinolaryngology, Head and Neck Surgery, Chang Gung Memorial Hospital, Medical College of Chang Gung University, Taoyuan 333, Taiwan.
Tzu-Chen YenDepartment of Nuclear Medicine and Molecular Imaging Center, Chang Gung Memorial Hospital, Medical College of Chang Gung University, Taoyuan 333, Taiwan.
Nai-Ming ChengDepartment of Nuclear Medicine and Molecular Imaging Center, Chang Gung Memorial Hospital, Medical College of Chang Gung University, Taoyuan 333, Taiwan.
Tsung-You TsaiDepartment of Otorhinolaryngology, Head and Neck Surgery, Chang Gung Memorial Hospital, Medical College of Chang Gung University, Taoyuan 333, Taiwan.
Shiao-Fwu TaiDepartment of Otorhinolaryngology, Head and Neck Surgery, Chang Gung Memorial Hospital, Medical College of Chang Gung University, Taoyuan 333, Taiwan.
Chi-Ying TsaiDepartment of Oral and Maxillofacial Surgery, Chang Gung Memorial Hospital, Medical College of Chang Gung University, Taoyuan 333, Taiwan.

Funding

Linkou Chang Gung Memorial Hospital CMRPG3I0011, CMRPG3I0013, CMRPG3I0012
6 · The paper itself

Abstract

(1) Background: The optimal cutoff value that maximizes the prognostic value of surgical margins in patients with resected oral cavity squamous cell carcinoma has not yet been identified. (2) Methods: Data for this study were retrieved from the Taiwan Cancer Registry Database. A total of 13,768 Taiwanese patients with oral cavity squamous cell carcinoma were identified and stratified according to different margin statuses (0, 0.1-4 and > 4 mm). The five-year local control, disease-specific survival and overall survival rates were the main outcome measures. (3) Results: The 5-year local control, disease-specific survival and overall survival rates of patients with close margins (0 and 0.1-4 mm) were significantly lower than those observed in patients with clear margins (> 4 mm; all

Indexed as

local controlnationwide registry studyoral cavity squamous cell carcinomaoutcomesurgical margin

Identifiers

PMID35008181
PMCPMC8749941

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.