ArticlePLoS biology2022
Analysis of ancestry heterozygosity suggests that hybrid incompatibilities in threespine stickleback are environment dependent.
Article in PLoS biology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed.
- Genetic Divergence in the Absence of Strong Ecological Differences Between Coexisting White and Common Atlantic Marine Stickleback.Ecology and evolution · 2026Article
- Article
- Nest architecture and male aggression drive sexual isolation between three-spined stickleback ecotypes.Zoological letters · 2026Article
- Coexistence in Sympatry With Gene Flow Before Speciation Has Completed.Molecular ecology · 2025Article
- A species interaction kick-starts ecological speciation in allopatry.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- How admixed captive breeding populations could be rescued using local ancestry information.Molecular ecology · 2025Article
- Limited Migration From Physiological Refugia Constrains the Rescue of Native Gastropods Facing an Invasive Predator.Evolutionary applications · 2024Article
- The Ecology of Hybrid Incompatibilities.Cold Spring Harbor perspectives in biology · 2024Review
- Recent secondary contact, genome-wide admixture, and asymmetric introgression of neo-sex chromosomes between two Pacific island bird species.PLoS genetics · 2024Article
- Coupling of Barriers to Gene Exchange: Causes and Consequences.Cold Spring Harbor perspectives in biology · 2024Review
- Swordtail fish hybrids reveal that genome evolution is surprisingly predictable after initial hybridization.PLoS biology · 2024Article
- Fisher's Geometric Model as a Tool to Study Speciation.Cold Spring Harbor perspectives in biology · 2024Review
- The extent of introgression between incipientProceedings of the National Academy of Sciences of the United States of America · 2024Article
- Genomic Approaches Are Improving Taxonomic Representation in Genetic Studies of Speciation.Cold Spring Harbor perspectives in biology · 2024Review
- Genome evolution is surprisingly predictable after initial hybridization.bioRxiv : the preprint server for biology · 2023Article
- Geographic destiny trumps taxonomy in the Roundtail Chub, Gila robusta species complex (Teleostei, Leuciscidae).Scientific reports · 2023Article
- The diverse effects of phenotypic dominance on hybrid fitness.Evolution; international journal of organic evolution · 2022Article
- Three problems in the genetics of speciation by selection.Proceedings of the National Academy of Sciences of the United States of America · 2022Article
- Heterosis counteracts hybrid breakdown to forestall speciation by parallel natural selection.Proceedings. Biological sciences · 2022Article
- One fish, two fish, red fish, dead fish: Detecting the genomic footprint of ecological incompatibilities.PLoS biology · 2022Article
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Abstract
Hybrid incompatibilities occur when interactions between opposite ancestry alleles at different loci reduce the fitness of hybrids. Most work on incompatibilities has focused on those that are "intrinsic," meaning they affect viability and sterility in the laboratory. Theory predicts that ecological selection can also underlie hybrid incompatibilities, but tests of this hypothesis using sequence data are scarce. In this article, we compiled genetic data for F2 hybrid crosses between divergent populations of threespine stickleback fish (Gasterosteus aculeatus L.) that were born and raised in either the field (seminatural experimental ponds) or the laboratory (aquaria). Because selection against incompatibilities results in elevated ancestry heterozygosity, we tested the prediction that ancestry heterozygosity will be higher in pond-raised fish compared to those raised in aquaria. We found that ancestry heterozygosity was elevated by approximately 3% in crosses raised in ponds compared to those raised in aquaria. Additional analyses support a phenotypic basis for incompatibility and suggest that environment-specific single-locus heterozygote advantage is not the cause of selection on ancestry heterozygosity. Our study provides evidence that, in stickleback, a coarse-albeit indirect-signal of environment-dependent hybrid incompatibility is reliably detectable and suggests that extrinsic incompatibilities can evolve before intrinsic incompatibilities.
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