Evidence map›Paper›PMID 35007132›Full record

ArticleAntimicrobial agents and chemotherapy2022

Azole-Resistant Alleles of

Bao Gia Vu, W Scott Moye-Rowley

Open access · greenAbstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
2.2field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 24 citations in OpenAlex.

  1. Article
  2. bioRxiv : the preprint server for biology · 2026
    Article
  3. Journal of medical microbiology · 2026
    Review
  4. Natural product based approaches to overcomeFrontiers in antibiotics · 2026
    Review
  5. Review
  6. Article
  7. Mechanism of azole resistance inJournal of medical microbiology · 2025
    Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. mSphere · 2024
    Article
  14. Similarities and distinctions in the activation of thebioRxiv : the preprint server for biology · 2024
    Article
  15. Article
  16. Article
  17. Comprehensive Overview ofJournal of microbiology and biotechnology · 2024
    Review
  18. Molecular Evaluation of the mRNA Expression of theJournal of fungi (Basel, Switzerland) · 2024
    Article
  19. Isobavachalcone exhibits antifungal and antibiofilm effects againstFrontiers in cellular and infection microbiology · 2024
    Article
  20. Current medical mycology · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Bao Gia VuDepartment of Molecular Physiology and Biophysics, Carver College of Medicine, University of Iowagrid.214572.7, Iowa City, Iowa, USA.
W Scott Moye-RowleyDepartment of Molecular Physiology and Biophysics, Carver College of Medicine, University of Iowagrid.214572.7, Iowa City, Iowa, USA.ORCID 0000-0002-7163-1120
University of Iowa · US

Funding

Genetic analysis of pleiotropic drug resistanceR01AI152494 · NIAID · UNIVERSITY OF IOWA · PI MOYE-ROWLEY, W SCOTT · 2020 to 2024
$2.1M
NIAID NIH HHS R01 AI152494
6 · The paper itself

Abstract

Azoles, the most commonly used antifungal drugs, specifically inhibit the fungal lanosterol α-14 demethylase enzyme, which is referred to as Erg11. Inhibition of Erg11 ultimately leads to a reduction in ergosterol production, an essential fungal membrane sterol. Many

Indexed as

AzolesCandida glabrataDNA-Binding ProteinsTranscription FactorsAllelesAntifungal AgentsDrug Resistance, FungalFungal ProteinsGene Expression Regulation, FungalMicrobial Sensitivity TestsAntifungal AgentsAzolesDNA-Binding ProteinsFungal ProteinsTranscription Factorsazole drugsCandida glabrataCdr1Erg11ergosterolPdr1transcriptional regulation

Identifiers

PMID35007132
PMCPMC8923186
OpenAlexW4205831762

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.