Evidence map›Paper›PMID 35007121›Full record

ReviewHealth psychology : official journal of the Division of Health Psychology, American Psychological Association2022

Posttraumatic stress disorder (PTSD), sleep, and cardiovascular disease risk: A mechanism-focused narrative review.

Corinne Meinhausen, Aric A Prather, Jennifer A Sumner

Abstract readReview
In one paragraph

Review in Health psychology : official journal of the Division of Health Psychology, American Psychological Association, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Observational
  4. Article
  5. Observational
  6. Review
  7. Functioning and disability consequences of comorbid posttraumatic stress disorder and diabetes in Vietnam era men and women veterans.Health psychology : official journal of the Division of Health Psychology, American Psychological Association · 2025
    Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Estradiol levels are differentially associated with pulse wave velocity in trauma-exposed premenopausal women with and without PTSD.American journal of physiology. Regulatory, integrative and comparative physiology · 2025
    Article
  13. Article
  14. Article
  15. Observational
  16. Observational
  17. Article
  18. Article
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Corinne MeinhausenDepartment of Psychology.ORCID 0000-0002-5906-1110
Aric A PratherDepartment of Psychiatry and Behavioral Sciences.
Jennifer A SumnerDepartment of Psychology.

Funding

Identifying Early Intervention Targets for Reducing Cardiovascular Risk in Posttraumatic StressR01HL139614 · NHLBI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI SUMNER, JENNIFER A · 2018 to 2022
$3.9M
Examining the reciprocal effects of racial discrimination and sleep on cardiovascular functioning: An experimental approachR01HL142051 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI PRATHER, ARIC ANDREW · 2018 to 2022
$3.5M
NHLBI NIH HHS R01 HL139614NHLBI NIH HHS R01 HL142051
6 · The paper itself

Abstract

objectiveGrowing longitudinal research has demonstrated that posttraumatic stress disorder (PTSD) precedes and predicts the onset of cardiovascular disease (CVD), and a number of physiological (e.g., dysregulation of the hypothalamic-pituitary-adrenal axis and autonomic nervous system, chronic systemic inflammation) and behavioral (e.g., physical inactivity, smoking, poor diet) factors might underlie this association. In this narrative review, we focus on sleep as a modifiable risk factor linking PTSD with CVD.

methodWe summarize the evidence for sleep disturbance after trauma exposure and the potential cardiotoxic effects of poor sleep, with an emphasis on mechanisms. In addition, we review the literature that has examined sleep in the context of the PTSD-CVD risk relation.

resultsAlthough sleep disturbance is a hallmark symptom of PTSD and a well-established risk factor for the development of CVD, the role of sleep in the association between PTSD and CVD has been largely unexamined in the extant literature. However, such work has the potential to improve our understanding of mechanisms of risk and inform intervention efforts to offset elevated CVD risk after trauma.

conclusionsWe outline several recommendations for future research and behavioral medicine models in order to help define and address the role of sleep behavior in the development of CVD among trauma-exposed individuals with PTSD. (PsycInfo Database Record (c) 2022 APA, all rights reserved).

Indexed as

Cardiovascular DiseasesSleep Wake DisordersStress Disorders, Post-TraumaticHumansHypothalamo-Hypophyseal SystemPituitary-Adrenal SystemSleep

Identifiers

PMID35007121
PMCPMC9271141

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.