Evidence map›Paper›PMID 35007092›Full record

ArticleJournal of consulting and clinical psychology2022

Changes in pain during buprenorphine maintenance treatment among patients with opioid use disorder and chronic pain.

Karlyn A Edwards, Kevin E Vowles, R Kathryn McHugh, Kamilla L Venner, Katie Witkiewitz

Abstract read
In one paragraph

Article in Journal of consulting and clinical psychology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact, top 100% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 0 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Karlyn A EdwardsDepartment of Anesthesiology, Preoperative, and Pain Medicine.ORCID 0000-0002-5821-3733
Kevin E VowlesSchool of Psychology.ORCID 0000-0003-4255-9067
R Kathryn McHughMcLean Hospital.
Kamilla L VennerDepartment of Psychology.ORCID 0000-0001-6404-4676
Katie WitkiewitzDepartment of Psychology.
McLean Hospital · USPain and Headache Center · US

Funding

The National Drug Abuse Treatment Clinical Trials Network (U10)U10DA015831 · NIDA · MC LEAN HOSPITAL (BELMONT, MA) · PI CARROLL, KATHLEEN M., WEISS, ROGER D. · 2002 to 2015
$28.8M
NIDA NIH HHS U10 DA015831
6 · The paper itself

Abstract

objectiveOpioid use disorder (OUD) and chronic pain frequently co-occur. Little is known about changes in pain during buprenorphine/naloxone (BUP/NX) maintenance and whether outcomes vary by pain levels. The present study examined changes in pain intensity and pain interference over 12 weeks of BUP/NX maintenance among participants with OUD and chronic pain (

methodData from Phase 2 of the Prescription Opioid Addiction Treatment Study (POATS) were used. Two latent transition models were conducted to characterize profiles and transitions between profiles of pain intensity or pain interference (estimated separately).

resultsEach model identified a high and low profile. In the pain interference model, the majority were classified in the low profile at baseline. In the pain intensity model, the majority were classified in the high profile at baseline. In both models, patients were more likely to remain in or transition to the low profiles by Week 12. Worse depression was associated with membership in the high pain interference profile at both timepoints. Women were more likely to be in the high pain intensity profile at baseline. Those in the high pain intensity and high pain interference profiles at Week 12 reported worse mental health quality of life (MH-QOL) at Week 12, as well as high pain intensity and high pain interference at Week 24.

conclusionsFor a subgroup of patients, high pain intensity and high pain interference remains unchanged during BUP/NX maintenance treatment. (PsycInfo Database Record (c) 2022 APA, all rights reserved).

Indexed as

BuprenorphineChronic PainOpioid-Related DisordersBuprenorphine, Naloxone Drug CombinationFemaleHumansNaloxoneNarcotic AntagonistsOpiate Substitution TreatmentQuality of LifeBuprenorphineBuprenorphine, Naloxone Drug CombinationNaloxoneNarcotic Antagonists

Identifiers

PMID35007092
PMCPMC12815489
OpenAlexW35007092

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.