Evidence map›Paper›PMID 35006825›Full record

ArticleACS applied bio materials2021

Patterned Electrospinning: A Method of Generating Defined Fibrous Constructs Influencing Cell Adhesion and Retention.

Daniel Palomares, Kaitlyn R Ammann, Javier J Saldana Perez, Alexan Gomez, Adriana Barreda, Andrew Russell-Cheung, Adriana Martin, Phat Le Tran, Sahir Hossainy, Rebecca C Slepian and 2 more

Abstract read
In one paragraph

Article in ACS applied bio materials, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Daniel PalomaresDepartment of Biomedical Engineering, University of Arizona, Tucson, Arizona 85721-0072, United States.
Kaitlyn R AmmannDepartment of Medicine, University of Arizona, Tucson, Arizona 85721-0072, United States.ORCID 0000-0002-8245-3796
Javier J Saldana PerezDepartment of Biomedical Engineering, University of Arizona, Tucson, Arizona 85721-0072, United States.
Alexan GomezDepartment of Biomedical Engineering, University of Arizona, Tucson, Arizona 85721-0072, United States.
Adriana BarredaDepartment of Biomedical Engineering, University of Arizona, Tucson, Arizona 85721-0072, United States.
Andrew Russell-CheungDepartment of Biological & Biomedical Sciences, University of Arizona, Tucson, Arizona 85721-0001, United States.
Adriana MartinSarver Heart Center, University of Arizona, Tucson, Arizona 85721-0001, United States.
Phat Le TranDepartment of Bioengineering, University of California, Berkeley, California 94720, United States.
Sahir HossainySarver Heart Center, University of Arizona, Tucson, Arizona 85721-0001, United States.
Rebecca C SlepianSarver Heart Center, University of Arizona, Tucson, Arizona 85721-0001, United States.
Syed F A HossainyDepartment of Bioengineering, University of California, Berkeley, California 94720, United States.
Marvin J SlepianDepartment of Biomedical Engineering, University of Arizona, Tucson, Arizona 85721-0072, United States.ORCID 0000-0002-7864-6691

Funding

Cardiovascular Biomedical Engineering Training GrantT32HL007955 · NHLBI · UNIVERSITY OF ARIZONA · PI BARTON, JENNIFER KEHLET · 2001 to 2020
$5.1M
NHLBI NIH HHS T32 HL007955
6 · The paper itself

Abstract

A critical component of tissue engineering is the ability to functionally replace native tissue stroma. Electrospinning is a technique capable of forming fibrous constructs with a high surface area for increased cell-material interaction and enhanced biocompatibility. However, physical and biological properties of electrospun scaffolds are limited by design controllability on a macroscale. We developed a methodology for generating electrospun scaffolds with defined patterns and topographic features to influence physical properties and biological interactions. Five unique design electrospinning target collectors were fabricated to allow for generation of defined polymeric scaffold patterns including lines, sinusoids, squares, zigzags, and solid. Poly(lactic-

Indexed as

Biocompatible MaterialsCell AdhesionCells, CulturedHumansHuman Umbilical Vein Endothelial CellsMaterials TestingParticle SizePolylactic Acid-Polyglycolic Acid CopolymerBiocompatible MaterialsPolylactic Acid-Polyglycolic Acid Copolymercell adhesionelectrospinningextracellular matrixfiber grammagepatterned targetsPLGAscaffoldstissue architecturetissue engineeringtissue stroma

Identifiers

PMID35006825
PMCPMC9444022

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.