Evidence map›Paper›PMID 35006650›Full record

ArticleCancer cytopathology2022

COVID-19 pandemic impact on cytopathology practice in the post-lockdown period: An international, multicenter study.

Elena Vigliar, Pasquale Pisapia, Filippo Dello Iacovo, Eduardo Alcaraz-Mateos, Greta Alì, Syed Z Ali, Zubair W Baloch, Claudio Bellevicine, Massimo Bongiovanni, Pavlina Botsun and 57 more

Abstract readMulticenter Study
In one paragraph

Article in Cancer cytopathology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

67 authors.

Elena VigliarDepartment of Public Health, University of Naples Federico II, Naples, Italy.
Pasquale PisapiaDepartment of Public Health, University of Naples Federico II, Naples, Italy.ORCID 0000-0002-6429-0620
Filippo Dello IacovoDepartment of Advanced Biomedical Sciences, University of Naples Federico II, Naples, Italy.
Eduardo Alcaraz-MateosPathology Department, Jose M. Morales Meseguer University General Hospital, Murcia, Spain.
Greta AlìDepartment of Surgical, Medical, and Molecular Pathology and Critical Care Medicine, University of Pisa, Pisa, Italy.
Syed Z AliDivision of Cytopathology, Department of Pathology, Johns Hopkins Hospital, Baltimore, Maryland.
Zubair W BalochDepartment of Pathology, University of Pennsylvania, Philadelphia, Pennsylvania.
Claudio BellevicineDepartment of Public Health, University of Naples Federico II, Naples, Italy.ORCID 0000-0002-7479-6457
Massimo BongiovanniCytopathology, SYNLAB Suisse SA, Lausanne, Switzerland.ORCID 0000-0001-9846-6682
Pavlina BotsunAnatomic Pathology, Laboratory of Pathology CSD, Kiev, Ukraine.
Dario BruzzeseDepartment of Public Health, University of Naples Federico II, Naples, Italy.
Lukas BubendorfInstitute of Pathology, University Hospital Basel, Basel, Switzerland.ORCID 0000-0001-5970-1803
Reinhard BüttnerDepartment of Pathology, University Hospital Cologne, Cologne, Germany.
Sule CanberkMedical Faculty, Institute of Molecular Pathology and Immunology, University of Porto, Porto, Portugal.ORCID 0000-0002-3736-1323
Arrigo CapitanioDepartment of Pathology, Linkoping University Hospital, Linkoping, Sweden.
Chiara CasadioDivision of Diagnostic Cytopathology, European Institute of Oncology IRCCS, Milan, Italy.
Eugeniu CazacuDepartment of Morphopathology, Nicolae Testemitanu State University of Medicine and Pharmacy, Chisinau, Moldova.
Beatrix Cochand-PriolletDepartment of Pathology, Cochin Hospital, Assistance Publique - Hôpitaux de Paris (APHP), University of Paris, Paris, France.
Alessandro D'AmuriAnatomic Pathology Unit, A. Perrino Hospital, Azienda Sanitaria Locale (ASL) Brindisi, Brindisi, Italy.
Katelynn DavisDivision of Cytopathology, Department of Pathology, Johns Hopkins Hospital, Baltimore, Maryland.
Catarina EloyMedical Faculty, Institute of Molecular Pathology and Immunology, University of Porto, Porto, Portugal.ORCID 0000-0001-7642-1280
Marianne EngelsDepartment of Pathology, University Hospital Cologne, Cologne, Germany.
Guido FaddaSection of Pathological Anatomy, Department of Human Pathology of Adult and Evolutive Age "Gaetano Barresi", G. Martino Hospital, Messina, Italy.
Gabriella FontaniniDepartment of Surgical, Medical, and Molecular Pathology and Critical Care Medicine, University of Pisa, Pisa, Italy.
Franco FulcinitiClinical Cytopathology Service, Histopathology Service, Cantonal Institute of Pathology, Locarno Cantonal Hospital, Locarno, Switzerland.
Paul HofmanLaboratory of Clinical and Experimental Pathology, Hospital-Related Biobank (BB-0033-00,025), FHU OncoAge, Pasteur Hospital, Nice, France.ORCID 0000-0003-0431-9353
Antonino IaccarinoDepartment of Public Health, University of Naples Federico II, Naples, Italy.
Antonio IeniSection of Pathological Anatomy, Department of Human Pathology of Adult and Evolutive Age "Gaetano Barresi", G. Martino Hospital, Messina, Italy.
Xiaoyin Sara JiangDepartment of Pathology, Duke University Medical Center, Durham, North Carolina.ORCID 0000-0002-3069-3130
Kennichi KakudoDepartment of Pathology, Izumi City General Hospital, Izumi, Japan.ORCID 0000-0002-0347-7264
Izidor KernDepartment of Pathology, University Clinic Golnik, Golnik, Slovenia.
Ivana KholovaDepartment of Pathology, Fimlab Laboratories, Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland.
Kathryn M Linton McDermottDepartment of Pathology and Cytology, Queen Alexandra Hospital, Portsmouth, United Kingdom.
Chinhua LiuDepartment of Pathology, The University of Texas MD Anderson Cancer Center, Houston, Texas.
Anandi LoboDepartment of Pathology, Kapoor Path Laboratories, Raipur, India.
Maria D LozanoDepartment of Pathology, University Clinic of Navarra, Pamplona, Spain.ORCID 0000-0002-6796-9380
Umberto MalapelleDepartment of Public Health, University of Naples Federico II, Naples, Italy.
Zahra MalekiDivision of Cytopathology, Department of Pathology, Johns Hopkins Hospital, Baltimore, Maryland.ORCID 0000-0003-3273-4802
Pamela MichelowDepartment of Anatomical Pathology, University of the Witwatersrand, National Health Laboratory Service, Johannesburg, South Africa.
Michael W MikulaDivision of Cytopathology, Department of Pathology, Johns Hopkins Hospital, Baltimore, Maryland.
Jamal MusayevDepartment of Pathology, Baku Pathology Center, Baku, Azerbaijan.
Gonca ÖzgünDepartment of Pathology, Baskent University Faculty of Medicine, Ankara, Turkey.
Meltem OznurDepartment of Pathology, Tekirdag Namik Kemal University, Suleymanpaşa/Tekirdag, Turkey.
Francisca Maria Peiró MarquésDepartment of Pathology, General University Hospital of Alicante, Alicante, Spain.
David PollerDepartment of Pathology and Cytology, Queen Alexandra Hospital, Portsmouth, United Kingdom.
Michal PyzlakAnatomic Pathology, Center for Diagnostic Pathology, Warsaw, Poland.
Betsy RobinsonDepartment of Pathology, Duke University Medical Center, Durham, North Carolina.
Esther Diana RossiDivision of Anatomic Pathology and Histology, Catholic University of Sacred Heart-University Polyclinic Foundation "A. Gemelli", Rome, Italy.ORCID 0000-0003-3819-4229
Sinchita Roy-ChowdhuriDepartment of Pathology, The University of Texas MD Anderson Cancer Center, Houston, Texas.ORCID 0000-0002-9447-7701
Mauro SaiegDepartment of Pathology, A. C. Camargo Cancer Center, Santa Casa Medical School, Sao Paulo, Brazil.ORCID 0000-0002-9438-226X
Spasenija Savic PrinceInstitute of Pathology, University Hospital Basel, Basel, Switzerland.
Fernando C SchmittMedical Faculty, Institute of Molecular Pathology and Immunology, University of Porto, Porto, Portugal.
Francisco Javier Seguí IváñezDepartment of Pathology, General University Hospital of Alicante, Alicante, Spain.
Tajana Štoos-VeićDepartment of Pathology and Cytology, University Hospital Dubrava, Zagreb, Croatia.
Oksana SulaievaAnatomic Pathology, Laboratory of Pathology CSD, Kiev, Ukraine.
Brenda J SweeneyDepartment of Pathology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts.
Giovanni TuccariSection of Pathological Anatomy, Department of Human Pathology of Adult and Evolutive Age "Gaetano Barresi", G. Martino Hospital, Messina, Italy.
Marie-Louise van VelthuysenDepartment of Pathology, Erasmus Medical Centre, Rotterdam, the Netherlands.
Paul A VanderLaanDepartment of Pathology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts.ORCID 0000-0002-7234-5652
Philippe VielhMedipath, American Hospital of Paris, Paris, France.
Patrizia ViolaNorth West London Pathology, Imperial College Healthcare, National Health Service Trust Charing Cross Hospital, London, United Kingdom.
Quirinus J M VoorhamAnatomic Pathology, Pathological Anatomical National Automated Archive (PALGA) Foundation, Houten, the Netherlands.
Birgit WeynandDepartment of Pathology, University Hospitals Leuven, Leuven, Belgium.
Pio ZeppaDepartment of Medicine and Surgery, University of Salerno, Fisciano, Italy.ORCID 0000-0001-7358-5925
William C FaquinDepartment of Pathology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts.ORCID 0000-0002-9043-7171
Martha Bishop PitmanDepartment of Pathology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts.
Giancarlo TronconeDepartment of Public Health, University of Naples Federico II, Naples, Italy.ORCID 0000-0003-1630-5805

Funding

Tumor Evolution and Metastasis ProgramP30CA016672 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI Scott Kopetz · 1985 to 2026
$290.8M
NCI NIH HHS P30 CA016672NIH HHS P30 CA016672
6 · The paper itself

Abstract

backgroundIn a previous worldwide survey, the authors showed a drastic reduction in the number of cytological specimens processed during the coronavirus disease 2019 "lockdown" period along with an increase in malignancy rates. To assess the continued impact of the pandemic on cytological practices around the world, they undertook a second follow-up worldwide survey collecting data from the post-lockdown period (2020).

methodsParticipants were asked to provide data regarding their cytopathology activity during the first 12 weeks of their respective national post-lockdown period (2020), which ranged from April 4 to October 31. Differences between the post-lockdown period and the corresponding 2019 period were evaluated, and the authors specifically focused on rates of malignant diagnoses.

resultsA total of 29 respondents from 17 countries worldwide joined the survey. Overall, a lower number of cytological specimens (n = 236,352) were processed in comparison with the same period in 2019 (n = 321,466) for a relative reduction of 26.5%. The overall malignancy rate showed a statistically significant increase (12,442 [5.26%] vs 12,882 [4.01%]; P < .001) during the same time period. Similar results were obtained if both malignancy and suspicious for malignancy rates were considered together (15,759 [6.58%] vs 16,011 [4.98%]; P < .001).

conclusionsThe data showed a persistent reduction in the cytological specimen volume during the post-lockdown period (2020). However, the relative increase in the cytological workload in the late part of the post-lockdown is a promising finding of a slow return to normality.

Indexed as

COVID-19NeoplasmsCommunicable Disease ControlHumansPandemicsSARS-CoV-2cancer screening programcoronavirus disease 2019 (COVID-19)cytopathologyfine-needle aspirationmalignancy rate

Identifiers

PMID35006650
PMCPMC9015399

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.