Evidence map›Paper›PMID 35006637›Full record

ArticleVeterinary and comparative oncology2022

Comparative gene expression study highlights molecular similarities between triple negative breast cancer tumours and feline mammary carcinomas.

Lara Sommerville, Jane Howard, Shane Evans, Pamela Kelly, Amanda McCann

Open access · hybridAbstract read
In one paragraph

Article in Veterinary and comparative oncology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.7field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 12 citations in OpenAlex.

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  9. [Comparative pathology in oncology-Best practice].Pathologie (Heidelberg, Germany) · 2024
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Lara SommervilleUCD Conway Institute of Biomolecular and Biomedical Research, University College Dublin, Dublin, Ireland.
Jane HowardUCD Conway Institute of Biomolecular and Biomedical Research, University College Dublin, Dublin, Ireland.ORCID https://orcid.org/0000-0001-6565-6877
Shane EvansUCD Conway Institute of Biomolecular and Biomedical Research, University College Dublin, Dublin, Ireland.
Pamela KellyUCD School of Veterinary Medicine, Veterinary Sciences Centre, University College Dublin, Dublin, Ireland.
Amanda McCannUCD Conway Institute of Biomolecular and Biomedical Research, University College Dublin, Dublin, Ireland.
University College Dublin · IE

Funding

The Mater Foundation, The Mater Misericordiae University HospitalUniversity College Dublin
6 · The paper itself

Abstract

Triple negative breast cancer (TNBC) is a rare, highly metastatic subtype of breast cancer that typically develops tumours of a high histological grade. As TNBC is negative for the oestrogen, progesterone and HER2 receptors it is also not eligible for targeted hormonal therapies. Therefore, those diagnosed with TNBC are faced with a very poor prognosis. Feline mammary carcinomas (FMCs) have been shown to share key characteristics of TNBC and are being investigated as novel animal models of this disease. A study by Granados-Soler et al., investigating prognostic markers of FMCs provided the basis of this research, and their prognostic value in TNBC was evaluated using a 'data-mining' research approach. Overall, the comparative genomic aspect of this research identified several potential prognostic markers translatable across TNBC and FMCs. These prognostic markers warrant further investigation in comparative oncology studies.

Indexed as

CarcinomaCat DiseasesMammary Neoplasms, AnimalTriple Negative Breast NeoplasmsAnimalsCatsGene ExpressionPrognosiscomparative oncologyfeline mammary carcinomagenomemolecular biologytriple negative breast cancer

Identifiers

PMID35006637
PMCPMC9303714
OpenAlexW4205473347

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.