Evidence map›Paper›PMID 35006367›Full record

SynthesisPediatric surgery international2022

"When to Nuss? patient age as a risk factor for complications of minimally invasive repair of pectus excavatum: a systematic review and meta-analysis".

Arielle C Coughlin, Sofia Ahsanuddin, Dani Inglesby, Conner Fox, Hope Xu, Ilana Margulies, Farah Sayegh, Celine Soudant, Henry S Sacks, Andrew Kaufman and 1 more

Abstract readMeta-AnalysisSystematic Review
PubMed Publisher
In one paragraph

Synthesis in Pediatric surgery international, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 2 pooled it
4.4field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 2 syntheses or guidelines pooled it, 22 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Bar-Related Infections After Minimally Invasive Repair of Pectus Excavatum: A 25-Year Single-Center Retrospective Cohort Study.European journal of pediatric surgery : official journal of Austrian Association of Pediatric Surgery ... [et al] = Zeitschrift fur Kinderchirurgie · 2026
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  6. Diagnosis and Management of Pectus Excavatum in Primary Care.Journal of the American Board of Family Medicine : JABFM · 2026
    Article
  7. Article
  8. Article
  9. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

Arielle C CoughlinDivision of Surgery, Icahn School of Medicine at Mount Sinai, One Gustave Levy Place, New York, NY, 10029, USA.ORCID http://orcid.org/0000-0002-1951-7849
Sofia AhsanuddinDivision of Surgery, Icahn School of Medicine at Mount Sinai, One Gustave Levy Place, New York, NY, 10029, USA.
Dani InglesbyDivision of Surgery, Icahn School of Medicine at Mount Sinai, One Gustave Levy Place, New York, NY, 10029, USA.
Conner FoxDivision of Surgery, Icahn School of Medicine at Mount Sinai, One Gustave Levy Place, New York, NY, 10029, USA.
Hope XuDivision of Surgery, Icahn School of Medicine at Mount Sinai, One Gustave Levy Place, New York, NY, 10029, USA.
Ilana MarguliesDivision of Surgery, Icahn School of Medicine at Mount Sinai, One Gustave Levy Place, New York, NY, 10029, USA.
Farah SayeghDivision of Surgery, Icahn School of Medicine at Mount Sinai, One Gustave Levy Place, New York, NY, 10029, USA.
Celine SoudantLevy Library, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Henry S SacksDepartment of Environmental Medicine and Public Health, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Andrew KaufmanDepartment of Thoracic Surgery, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Peter J TaubDivision of Surgery, Icahn School of Medicine at Mount Sinai, One Gustave Levy Place, New York, NY, 10029, USA. Peter.taub@mountsinai.org.
Icahn School of Medicine at Mount Sinai · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe optimal age for minimally invasive repair of pectus excavatum (MIRPE) is unclear; this study investigates the differences in complication rates among different age groups undergoing repair.

methodsPubMed and Embase databases were searched from inception to October 2020. To assess age as a risk factor for complications, odds ratios from relevant studies were analyzed using the Mantel-Haenszel method with a random-effects model for younger vs older patients. Specific complication rates were compared between the two cohorts using a chi-squared test.

resultsOf the 4448 studies retrieved, 25 studies stratified complication data by age groups. From these studies, ten studies compared groups at ages < 18 and ≥ 18 and four studies compared ages < 20 and ≥ 20, and one study compared ages < 19 and ≥ 19. These fifteen studies reported on 5978 patients, with 1188 complications, for a complication rate of 19.87%. Older patients were more likely to have complications in a pooled analysis of studies comparing older vs younger patients (OR = 1.66, 95% CI = 1.28-2.14, heterogeneity I

conclusionIncreased age is a risk factor for complications of MIRPE. This supports repair of pectus excavatum prior to late adolescence.

Indexed as

Funnel ChestThoracoplastyAdolescentHumansMinimally Invasive Surgical ProceduresPostoperative ComplicationsReoperationRetrospective StudiesRisk FactorsTreatment OutcomeChest wallMIRPENussPectus excavatumPlastic surgeryReconstructive surgery

Identifiers

PMID35006367
OpenAlexW4206550219

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.