ReviewHerzschrittmachertherapie & Elektrophysiologie2022
Late arrhythmia recurrence after atrial fibrillation ablation: incidence, mechanisms and clinical implications.
Review in Herzschrittmachertherapie & Elektrophysiologie, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers, 6 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
45 citing papers in PubMed, 6 syntheses or guidelines pooled it, 70 citations in OpenAlex.
- Effect of Post-Ablational Angiotensin Receptor-Neprilysin Inhibitor on Atrial Fibrillation Recurrence: A Systematic Review and Meta-Analysis in Asian Population.Clinical cardiology · 2026Pooled it
- Pooled it
- Association of glucagon-like peptide-1 receptor agonists with atrial fibrillation recurrence after catheter ablation: a systematic review and meta-analysis.Frontiers in cardiovascular medicine · 2026Pooled it
- Pooled it
- Circulating soluble suppression of tumorigenicity-2 and the recurrence of atrial fibrillation after catheter ablation: A meta-analysis.Biomolecules & biomedicine · 2024Pooled it
- Left atrial appendage flow velocity predicts recurrence of atrial fibrillation after catheter ablation: A systematic review and meta-analysis.Frontiers in cardiovascular medicine · 2022Pooled it
- NT-proBNP as a Predictor of Atrial Fibrillation Recurrence After Cryoballoon, Radiofrequency and Pulsed-Field Ablation.Pacing and clinical electrophysiology : PACE · 2026Article
- Right atrioventricular coupling index predicts adverse outcomes in patients with non-valvular atrial fibrillation undergoing catheter ablation: an echocardiography insight.The international journal of cardiovascular imaging · 2026Article
- Association of Hypothyroidism With Atrial Substrate Burden and Recurrence Following Catheter Ablation of Atrial Fibrillation.Korean circulation journal · 2026Article
- Impact of acute rhythm restoration strategy on atrial fibrillation recurrence after cryoballoon ablation: a real-world cohort study.BMC cardiovascular disorders · 2026Article
- Observational
- Left atrial anterior scar in persistent atrial fibrillation: Results with pulmonary vein isolation and linear ablation including posterior mitral line.Heart rhythm O2 · 2026Article
- Predictive factors for atrial fibrillation recurrence after radiofrequency ablation: a multifactorial approach.BMC cardiovascular disorders · 2026Article
- Toward Standardized Methodologies for Drug-Induced Proarrhythmia Classification: An In Silico Proof of Concept.Computational and structural biotechnology journal · 2026Article
- Oxidative Stress, Mitochondrial Homeostasis, and Sirtuins in Atrial Fibrillation.International journal of molecular sciences · 2025Review
- Optimum Patient's Selection for Atrial Fibrillation Ablation Using Echocardiography.Diagnostics (Basel, Switzerland) · 2025Review
- The Predictive Value of Real-World Cardiologist Performance (RWCP) Score in Atrial Fibrillation Recurrence Risk After Radiofrequency Ablation.Journal of cardiovascular electrophysiology · 2025Article
- Serial electrical cardioversion for refractory atrial fibrillation with rapid ventricular response post ablation.International journal of emergency medicine · 2025Article
- The risk factors of atrial substrate remodeling in the patients of paroxysmal atrial fibrillation following pulmonary vein isolation.BMC cardiovascular disorders · 2025Article
- Risk factors and nomogram prediction model for recurrence after radiofrequency ablation in patients with persistent atrial fibrillation.BMC cardiovascular disorders · 2025Article
Corrections and comments
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Authors and funding
3 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND AND
objectivesCatheter ablation of atrial fibrillation (AF) has become a well-established and widely used therapy, with pulmonary vein isolation (PVI) being the key modality of ablation. However, arrhythmia recurrences after PVI are common, with a relevant number of patients undergoing repeat ablation. Arrhythmia recurrence after PVI may vary regarding time point and mode of recurrence. While early arrhythmia recurrences of AF after PVI are mostly found to be the product of electrical reconnection of the pulmonary veins, the exact mechanisms of very late arrhythmia recurrence, occurring later than 12 months after successful PVI, remain unclear. This review provides an overview on the current evidence on time point and mechanisms of arrhythmia recurrence after PVI focussing on late arrhythmia recurrence. RECENT
findingsThe incidence of late arrhythmia recurrence after PVI can lie at a rate of up to 30% according to long-term follow-up studies. Mechanisms of recurrence include electrical reconnection of previously isolated pulmonary veins and development of atrial fibrosis. The use of cryoballoon ablation is likely to be more effective in reducing late arrhythmia recurrences compared to radiofrequency ablation. Novel scores such as the MB-LATER score or the APPLE score may become useful tools in predicting arrhythmia recurrence after PVI. RESULTS AND
conclusionLate arrhythmia recurrence after PVI is common and leads to a relevant impairment of long-term success. Relevant data are currently limited and exact mechanisms of arrhythmia recurrence remain unclear. Further studies are needed to elucidate pathogenetic mechanisms of late arrhythmia recurrence after PVI in order to improve treatment strategies.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.