Evidence map›Paper›PMID 35006326›Full record

SynthesisWorld journal of surgery2022

Effects of Gastric Bypass and Sleeve Gastrectomy on Bone Mineral Density and Bone Turnover Markers: A Systematic Review and Meta-Analysis.

Mohamed AbdAlla Salman, Mohammed Aradaib, Ahmed Salman, Ahmed Elewa, Mohamed Tourky, Hossam El-Din Shaaban

Abstract readMeta-AnalysisSystematic Review
PubMed Publisher
In one paragraph

Synthesis in World journal of surgery, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 2 pooled it
2.6field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 2 syntheses or guidelines pooled it, 14 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Review
  6. Review
  7. Observational
  8. The Short-Term Impact of Sleeve Gastrectomy on Bone Health.Mediterranean journal of rheumatology · 2025
    Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 2 countries.

Mohamed AbdAlla SalmanGeneral Surgery Department, Kasralainy School of Medicine, Cairo University, Cairo, Egypt. Mohammed.salman@kasralainy.edu.eg.ORCID http://orcid.org/0000-0001-5445-6415
Mohammed AradaibGeneral Surgery Department, Sunderland Royal Hospital, Sunderland, Tyne and Wear, UK.
Ahmed SalmanInternal Medicine Department, Kasr Alainy Faculty of Medicine, Cairo University, Cairo, Egypt.
Ahmed ElewaGeneral Surgery Department Department, National Hepatology and Tropical Medicine Research Institute, Cairo, Egypt.
Mohamed TourkyGeneral Surgery Department, Great Western Hospital, NHS Foundation Trust, Swindon, UK.
Hossam El-Din ShaabanGastroenterology and Hepatology Department, National Hepatology and Tropical Medicine Research Institute, Cairo, Egypt.
Cairo University · EGNational Water Research Center · EGGreat Western Hospital · GBSunderland Royal Hospital · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThere is a growing interest in the post-operative bone-related effects of bariatric surgery. However, little is known about the comparative effects of the most commonly performed bariatric procedures, namely Roux-en-Y gastric bypass (RYGB) and sleeve gastrectomy (SG).

objectivesTo systematically assess the differences in areal bone mineral density (aBMD) and biochemical and hormonal markers of bone metabolism among patients undergoing RYGB and SG.

methodsWe conducted a systematic review and meta-analysis of studies aBMD at different sites, as well as bone-specific alkaline phosphatase (BALP), 25-OH-vitamin D, calcium and parathyroid hormone (PTH) after RYGB and SG.

resultsFourteen studies were included (717 patients, 50.63% in the RYGB arm). Based on data collected at 1 year, 2 years and > 2 years, there were no significant differences in aBMD measurements at the total hip, lumbar spine, femoral neck, and the whole body with no statistical heterogeneity among different comparisons. Patients in the RYGB group showed significantly higher concentrations of BALP at 1 year (SMD = 0.52, 95%CI, 0.23-0.81, p = 0.0004) and PTH at > 2 years of follow-up (SMD = 0.68, 95%CI, 0.31-1.05, p = 0.0003) compared to the SG group.

conclusionThere were no significant differences in aBMD measurements at the hip, lumbar spine, femoral neck, and the total body following RYGB and SG procedures. However, BALP and PTH concentrations were significantly higher after RYGB surgeries compared to SG. Attention should be paid to patients undergoing RYGB to prevent the expected skeletal fragility over time.

Indexed as

Gastric BypassObesity, MorbidBone DensityBone RemodelingGastrectomyHumansParathyroid HormoneTreatment OutcomeParathyroid Hormone

Identifiers

PMID35006326
OpenAlexW4206122518

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.