ArticleThe journal of physical chemistry letters2022
Vesicles Balance Osmotic Stress with Bending Energy That Can Be Released to Form Daughter Vesicles.
Article in The journal of physical chemistry letters, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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15 citing papers in PubMed, 39 citations in OpenAlex.
- Polymer-Coated Nanoarchitectonics of Titanium Dioxide Nanoparticles with Enhanced Antimicrobial Activity: Mechanistic Insights into Localized Particle-Membrane Interactions.ACS central science · 2026Article
- Orchestrating Self-Replication in Artificial Cells with Digital Microfluidics.Small (Weinheim an der Bergstrasse, Germany) · 2025Article
- Dynamic Shape Modulation of Deflated and Adhered Lipid Vesicles.Journal of the American Chemical Society · 2025Article
- Formation of Multispheres and Myelin Based on Multiple Solutions of Membrane Shape Equation.Membranes · 2025Article
- Supplementation of Trimethylamine N-Oxide or Betaine in Semen Improves Quality of Boar Spermatozoa Stored at 17 °C Following Hydrostatic Pressure Stress.Life (Basel, Switzerland) · 2025Article
- Characterization of Aquaporin Z proteoliposome structure and functionality via microscopy and scattering methods.European biophysics journal : EBJ · 2025Article
- Dynamic membrane changes and osmotic effects by sugar alcohols.NPJ science of food · 2025Article
- Synthetic Lipid Biology.Chemical reviews · 2025Review
- Shape of the membrane neck around a hole during plasma membrane repair.Biophysical journal · 2024Article
- Artificial cells for in vivo biomedical applications through red blood cell biomimicry.Nature communications · 2024Review
- Shocker─A Molecular Dynamics Protocol and Tool for Accelerating and Analyzing the Effects of Osmotic Shocks.Journal of chemical theory and computation · 2024Article
- A colloidal viewpoint on the sausage catastrophe and the finite sphere packing problem.Nature communications · 2023Article
- A Note on Vestigial Osmotic Pressure.Membranes · 2023Article
- Article
- On the osmotic pressure of cells.QRB discovery · 2022Article
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Authors and funding
4 authors at 1 institution in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
The bending energy of the lipid membrane is central to biological processes involving vesicles, such as endocytosis and exocytosis. To illustrate the role of bending energy in these processes, we study the response of single-component giant unilamellar vesicles (GUVs) subjected to external osmotic stress by glucose addition. For osmotic pressures exceeding 0.15 atm, an abrupt shape change from spherical to prolate occurs, showing that the osmotic pressure is balanced by the free energy of membrane bending. After equilibration, the external glucose solution was exchanged for pure water, yielding rapid formation of monodisperse daughter vesicles inside the GUVs through an endocytosis-like process. Our theoretical analysis shows that this process requires significant free energies stored in the deformed membrane to be kinetically allowed. The results indicate that bending energies stored in GUVs are much higher than previously implicated, with potential consequences for vesicle fusion/fission and the osmotic regulation in living cells.
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