Evidence map›Paper›PMID 35005709›Full record

ReviewBiophysics reviews2021

Graphene nanostructures for input-output bioelectronics.

Raghav Garg, Daniel San Roman, Yingqiao Wang, Devora Cohen-Karni, Tzahi Cohen-Karni

Abstract readReview
In one paragraph

Review in Biophysics reviews, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Review
  6. Article
  7. Review
  8. Article
  9. Nanoenabled Bioelectrical Modulation.Accounts of materials research · 2021
    Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Raghav GargDepartment of Materials Science and Engineering, Carnegie Mellon University, Pittsburgh, Pennsylvania 15213, USA.ORCID https://orcid.org/0000-0002-3501-6892
Daniel San RomanDepartment of Materials Science and Engineering, Carnegie Mellon University, Pittsburgh, Pennsylvania 15213, USA.ORCID https://orcid.org/0000-0003-3133-1446
Yingqiao WangDepartment of Materials Science and Engineering, Carnegie Mellon University, Pittsburgh, Pennsylvania 15213, USA.ORCID https://orcid.org/0000-0002-9294-3705
Devora Cohen-KarniPreclinical education biochemistry, Lake Erie College of Osteopathic Medicine at Seton Hill, Greensburg, Pennsylvania 15601, USA.ORCID https://orcid.org/0000-0002-8049-2492

Funding

Hybrid-nanomaterials for non-genetic optical stimulation of excitable cellsR21EB029164 · NIBIB · CARNEGIE-MELLON UNIVERSITY · PI COHEN-KARNI, TZAHI · 2020 to 2021
$397k
NIBIB NIH HHS R21 EB029164
6 · The paper itself

Abstract

The ability to manipulate the electrophysiology of electrically active cells and tissues has enabled a deeper understanding of healthy and diseased tissue states. This has primarily been achieved via input/output (I/O) bioelectronics that interface engineered materials with biological entities. Stable long-term application of conventional I/O bioelectronics advances as materials and processing techniques develop. Recent advancements have facilitated the development of graphene-based I/O bioelectronics with a wide variety of functional characteristics. Engineering the structural, physical, and chemical properties of graphene nanostructures and integration with modern microelectronics have enabled breakthrough high-density electrophysiological investigations. Here, we review recent advancements in 2D and 3D graphene-based I/O bioelectronics and highlight electrophysiological studies facilitated by these emerging platforms. Challenges and present potential breakthroughs that can be addressed via graphene bioelectronics are discussed. We emphasize the need for a multidisciplinary approach across materials science, micro-fabrication, and bioengineering to develop the next generation of I/O bioelectronics.

Identifiers

PMID35005709
PMCPMC8717360

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.