Evidence map›Paper›PMID 35005602›Full record

ArticleInfection prevention in practice2022

Point-prevalence surveys of antimicrobial consumption and resistance at a paediatric and an adult tertiary referral hospital in Yangon, Myanmar.

Win Thandar Oo, Samuel D Carr, Christian S Marchello, Moe Moe San, Aung Tun Oo, Khine Mar Oo, Kay Thi Lwin, Hla Hla Win, John A Crump

Open access · goldAbstract read
In one paragraph

Article in Infection prevention in practice, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
1.8field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it, 15 citations in OpenAlex.

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  10. Three-Year Point Prevalence Survey of Antimicrobial Use in a Chinese University Hospital.The Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 2 countries.

Win Thandar OoCentre for International Health, University of Otago, Dunedin, New Zealand.
Samuel D CarrCentre for International Health, University of Otago, Dunedin, New Zealand.
Christian S MarchelloCentre for International Health, University of Otago, Dunedin, New Zealand.
Moe Moe SanDepartment of Tropical and Infectious Diseases Medicine, Yangon General Hospital, Yangon, Myanmar.
Aung Tun OoYangon Children's Hospital, Yangon, Myanmar.
Khine Mar OoDepartment of Microbiology, University of Medicine 1, Yangon, Myanmar.
Kay Thi LwinDepartment of Preventive and Social Medicine, University of Medicine 1, Yangon, Myanmar.
Hla Hla WinUniversity of Public Health, Yangon, Myanmar.
John A CrumpCentre for International Health, University of Otago, Dunedin, New Zealand.
University Of Medicine 1 Yangon · MMUniversity of Otago · NZEast Yangon General Hospital · MMUniversity of Public Health Yangon · MMYangon Children's Hospital · MM

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAntimicrobial resistance is increasingly prevalent worldwide. The inappropriate use of antimicrobials, including in the hospital setting, is considered a major driver of antimicrobial resistance.

aimTo inform improvements in antimicrobial stewardship, we undertook point prevalence surveys of antimicrobial prescribing at Yangon Children's Hospital and Yangon General Hospital in Yangon, Myanmar.

methodsWe conducted our surveys using the Global Point-Prevalence Survey of Antimicrobial Consumption and Resistance (Global-PPS) method. All inpatients who were prescribed an antimicrobial on the day of the survey were included in the analysis.

findingsWe evaluated a total of 1,980 patients admitted to two hospitals during December 2019. Of these, 1,255 (63.4%) patients were prescribed a total of 2,108 antimicrobials. Among antimicrobials prescribed, 722 (34.3%) were third-generation cephalosporins, the most commonly prescribed antimicrobial class. A total of 940 (44.6%) antimicrobials were prescribed for community-acquired infection, and 724 (34.3%) for surgical prophylaxis. Of 2,108 antimicrobials, 317 (15.0%) were prescribed for gastrointestinal tract prophylaxis, 305 (14.5%) for skin, soft tissue, bone and joint prophylaxis, and 303 (14.4%) for pneumonia treatment. A stop or review date was documented for 350 (16.6%) antimicrobial prescriptions, 673 (31.9%) antimicrobial prescriptions were guideline compliant, and 1,335 (63.3%) antimicrobials were administered via the parenteral route. Of 1,083 antimicrobials prescribed for a therapeutic use, 221 (20.4%) were targeted therapy.

conclusionOur findings underscore the need to update and expand evidence-based guidelines for antimicrobial use, promote the benefits of targeted antimicrobial therapy, and support the implementation of hospital-based antimicrobial stewardship programmes at the hospitals surveyed.

Indexed as

Antimicrobial resistanceAntimicrobial stewardshipMyanmarProphylaxisQuality indicatorsTreatment

Identifiers

PMID35005602
PMCPMC8717234
OpenAlexW4200340648

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.