Evidence map›Paper›PMID 35005589›Full record

ReviewJournal of translational autoimmunity2021

Diagnosis and treatment of eosinophilic myocarditis.

Zezhong Zhong, Zicong Yang, Yiming Peng, Lei Wang, Xuming Yuan

Open access · goldAbstract readReview
In one paragraph

Review in Journal of translational autoimmunity, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers.

0numbers the graph read from it
0cells of the map it votes in
46citing papers in PubMed
6.5field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

46 citing papers in PubMed, 55 citations in OpenAlex.

  1. Eosinophilia and the Heart: Evolving Concepts.Current cardiology reports · 2026
    Review
  2. Article
  3. AlEuropean journal of nuclear medicine and molecular imaging · 2026
    Article
  4. Review
  5. Review
  6. Review
  7. Review
  8. Article
  9. Article
  10. Review
  11. Review
  12. Multimodality Imaging in Eosinophilic Myocarditis: A Rare Cause of Heart Failure.Journal of cardiovascular development and disease · 2025
    Review
  13. Article
  14. Review
  15. Review
  16. Article
  17. Article
  18. Article
  19. Eosinophilic Myocarditis: A Concise Review.Current cardiology reports · 2025
    Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Zezhong ZhongDepartment of Cardiology, Liuyang People's Hospital, Nanhua University, Hunan Province, 410300, China.
Zicong YangPeople's Hospital of Guangxi Zhuang Autonomous Region, 530021, China.
Yiming PengDepartment of Cardiology, Liuyang People's Hospital, Nanhua University, Hunan Province, 410300, China.
Lei WangDepartment of Cardiology, Liuyang People's Hospital, Nanhua University, Hunan Province, 410300, China.
Xuming YuanDepartment of Cardiology, Liuyang People's Hospital, Nanhua University, Hunan Province, 410300, China.
The People's Hospital of Guangxi Zhuang Autonomous Region · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Eosinophilic myocarditis is a type of inflammatory cardiomyopathy characterized by eosinophilic infiltration into myocardial tissue. The accurate myocarditis incidence rate is difficult to determine because of the clinical limitations of an endomyocardial biopsy. The primary pathogenesis of eosinophilic myocarditis is the release of related substances by eosinophils, leading to cell membrane damage and cell destruction. However, evidence suggests that specific genes play a role in myocarditis development.As CMR imaging availability increases, the diagnosis rate of eosinophilic myocarditis will increase. The diagnosis of myocarditis mainly depends on an endocardial biopsy. Glucocorticoids can relieve patients' symptoms, but the early use of steroids may prevent intermediate disease stage development (i.e., thrombonecrosis and fibrosis with wall thrombosis). Anticoagulant therapy may also affect disease development. In addition to routine follow-up, a regular myocardial biopsy should be considered for discharged patients, if possible.

Indexed as

ANCA, anti-neutrophil cytoplasmic antibodyCardiac magnetic resonanceCEL, chronic eosinophilic leukemia.CMR, cardiac magnetic resonanceEAM, experimental autoimmune myocarditisECG, electrocardiogramECP, eosinophilic cationic proteinEGE, early gadolinium enhancement, LGE, late gadolinium enhancementEGPA, eosinophilic granulomatosis with polyangiitisEMB, endomyocardial biopsyEndomyocardial biopsyEosinophilic myocarditisFIP1L1-PDGFRA, FIP1-like1-platelet-derived growth factor receptor αGlucocorticoidsHES, hypereosinophilic syndromeIFNγ, interferon gamma

Identifiers

PMID35005589
PMCPMC8716607
OpenAlexW3196349822

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.