Evidence map›Paper›PMID 35005513›Full record

ArticleBeyoglu eye journal2021

Evaluation of Serum Concentration of the Myokine Irisin (FNDC5) in Patients with Age-Related.

Burak Turgut, Kadir Mercan, Nevin Ilhan, Selahattin Semih Aydogan

Open access · diamondAbstract read
In one paragraph

Article in Beyoglu eye journal, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 88% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Burak TurgutDepartment of Ophthalmology, Onsekiz Mart University Faculty of Medicine, Canakkale, Turkey.ORCID https://orcid.org/0000-0002-5393-0557
Kadir MercanDepartment of Ophthalmology, Private Sevgi Hospital, Malatya, Turkey.ORCID https://orcid.org/0000-0001-9559-7556
Nevin IlhanDepartment of Biochemistry, Firat University Faculty of Medicine, Elazig, Turkey.ORCID https://orcid.org/0000-0002-0208-8929
Selahattin Semih AydoganDepartment of Ophthalmology, Yuksek Ihtisas University Faculty of Medicine, Ankara, Turkey.ORCID https://orcid.org/0000-0002-5642-8706
Çanakkale Onsekiz Mart Üniversitesi · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThis study evaluated the serum irisin level of patients with age-related macular degeneration (ARMD) and compared it with that of healthy individuals.

methodsThe serum irisin level of 15 healthy controls (Group 1) and 15 dry ARMD patients (Group 2) and 15 wet ARMD patients (Group 3) were measured using the enzyme-linked immunosorbent assay (ELISA) method and compared.

resultsThere was no statistically significant difference between the groups in terms of age or gender (p>0.05). The mean serum irisin levels of Group 1, Group 2, and Group 3 were 25.81±24.04 ng/mL, 22.93±19.05 ng/mL, and 12.38±8.16 ng/mL, respectively. Although the mean irisin level in the wet ARMD patients was lower than that of the control and dry ARMD groups, there was no statistically significant difference between the groups (p>0.05).

conclusionThe results suggest that the serum irisin level in ARMD patients is not different from that of healthy individuals. Studies of larger groups that examine the irisin level in the vitreous and neovascular membranes will further elucidate any role in the pathogenesis of ARMD.

Indexed as

Age-related macular degenerationdryFNDC5irisinserum levelwet

Identifiers

PMID35005513
PMCPMC8697044
OpenAlexW3190699743

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.