ReviewCanadian journal of pain = Revue canadienne de la douleur2018
A systematic review of strategies to improve appropriate use of opioids and to reduce opioid use disorder and deaths from prescription opioids.
Review in Canadian journal of pain = Revue canadienne de la douleur, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 2 syntheses or guidelines pooled it, 36 citations in OpenAlex.
- Healthcare Practitioner and Other Professionals' Perspectives on Gabapentinoid Misuse and Dependence: A Systematic Review of Qualitative Studies.European journal of pain (London, England) · 2025Pooled it
- Evaluation of Interventions to Reduce Opioid Prescribing for Patients Discharged From the Emergency Department: A Systematic Review and Meta-analysis.JAMA network open · 2022Pooled it
- Chronic Disease and Disability in the United States: Trends, Inequities, and Imperatives for Policy Reform.The Milbank quarterly · 2026Article
- A Cross-Sectional Study of Acceptability and Influence of HEALing Communities Study Communications Campaign Messaging Among Community Members in Four U.S. States.American journal of health promotion : AJHP · 2026Article
- Smartphone-Based Ecological Momentary Assessment to Monitor Opioid Use and Overdose Among People Who Use Opioids: Prospective Observational Feasibility Study.JMIR human factors · 2026Observational
- Opioid Message Fatigue in the United States: Prevalence and Associations with Stigma and Policy Support.Substance use & misuse · 2026Article
- Awareness about opioids crisis, policies and regulation of opioid stewardship at hospitals settings: a nationwide cross-sectional study among healthcare professionals from Pakistan.Substance abuse treatment, prevention, and policy · 2026Article
- Reducing opioid prescriptions does not increase rate of refills or new opioid requests: evidence from a randomized trial.Health affairs scholar · 2026Article
- Healthcare provider knowledge, beliefs, and attitudes regarding opioids for chronic non-cancer pain in North America prior to the emergence of COVID-19: A systematic review of qualitative research.Canadian journal of pain = Revue canadienne de la douleur · 2023Review
- Strategies to prevent long-term opioid use following trauma: a Canadian practice survey.Canadian journal of anaesthesia = Journal canadien d'anesthesie · 2023Article
- A bifurcated opioid treatment system and widening insidious disparities.Addictive behaviors · 2022Article
- Strategies aimed at preventing long-term opioid use in trauma and orthopaedic surgery: a scoping review.BMC musculoskeletal disorders · 2022Article
- Evaluations of Continuing Health Provider Education Focused on Opioid Prescribing: A Scoping Review.Academic medicine : journal of the Association of American Medical Colleges · 2022Article
- Chronic Pain and Opioid Prescribing: Three Ways for Navigating Complexity at the Clinical‒Population Health Interface.American journal of public health · 2022Article
- A retrospective quantitative implementation evaluation of Safer Opioid Prescribing, a Canadian continuing education program.BMC medical education · 2021Article
- Health communication campaigns to drive demand for evidence-based practices and reduce stigma in the HEALing communities study.Drug and alcohol dependence · 2020Article
- Strategies aimed at preventing chronic opioid use in trauma and acute care surgery: a scoping review protocol.BMJ open · 2020Article
- Improving opioid guideline adherence: evaluation of a multifaceted, theory-informed pilot intervention for family physicians.BMJ open · 2020Article
- 'Communities are attempting to tackle the crisis': a scoping review on community plans to prevent and reduce opioid-related harms.BMJ open · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAbuse of prescription opioids is a serious problem in North America.
aimsThe aim of this study was to conduct a systematic review of peer-reviewed and grey literature to examine existing strategies aimed at improving the appropriate use of prescription opioids and/or reducing the misuse, abuse, and diversion of these drugs.
methodsThe following electronic databases were searched to September 2015 without language restrictions: MEDLINE, EMBASE, PsycINFO, and CINAHL; the grey literature was searched to May 2014. Reference lists of retrieved papers were also searched. Studies were eligible if a strategy was implemented and its impact on at least one of the primary outcomes of interest (appropriate prescription opioid use; misuse, abuse, opioid use disorder, diversion; overdose) was measured. Standardized, prepiloted forms were used for relevance screening, quality appraisal, and data extraction.
resultsA total of 65 studies that assessed 66 distinct strategies were identified. Due to the heterogeneity of the strategies, a qualitative synthesis was conducted. Many studies combined more than one type of strategy and measured various types of outcomes. The strategies with most promising results involved education, clinical practices, collaborations, prescription monitoring programs, public campaigns, opioid substitution programs, and naloxone distribution. We also found strategies that had some unintended consequences after implementation.
conclusionsOur review identified successful strategies that have been implemented and evaluated in various jurisdictions. There is a need to replicate and disseminate these strategies where the problem of prescription opioid misuse and abuse has taken a toll on society.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.