ArticleKidney international reports2022
Impact of Pregnancy on GFR Decline and Kidney Histology in Kidney Transplant Recipients.
Article in Kidney international reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed, 1 synthesis or guideline pooled it, 22 citations in OpenAlex.
- Long-term impact of pregnancy on mortality and graft outcomes in kidney transplant recipients: a systematic review and meta-analysis.International urology and nephrology · 2025Pooled it
- Kidney Replacement Therapy Within 12 Months of Childbirth in Australia.Kidney international reports · 2026Article
- Beyond the first pregnancy: learning from the history of a kidney transplant recipient who experienced five pregnancies.Journal of nephrology · 2025Article
- A Systematic Review on the Impact of Pregnancy on Renal Graft Function.Journal of clinical medicine · 2025Review
- Dialysis During Pregnancy: Are We Any Closer to Clarity?Kidney international reports · 2025Article
- Maternal and neonatal outcomes in kidney transplant recipients: a single-center observational study.Wiener klinische Wochenschrift · 2025Observational
- Late pregnancy in women with renal transplants: A multidisciplinary guide.Obstetric medicine · 2024Review
- Pregnancy History and Kidney Disease Progression Among Women Enrolled in Cure Glomerulonephropathy.Kidney international reports · 2023Article
- Pregnancy after Kidney Transplantation-Impact of Functional Renal Reserve, Slope of eGFR before Pregnancy, and Intensity of Immunosuppression on Kidney Function and Maternal Health.Journal of clinical medicine · 2023Article
- Response to "New Biomarker of Preeclampsia in Kidney Transplant Recipients".Kidney international reports · 2023Article
- New Biomarker of Preeclampsia in Kidney Transplant Recipients.Kidney international reports · 2023Article
- Sex-specific time trends of long-term graft survival after kidney transplantation - a registry-based study.Renal failure · 2023Article
- Parenthood With Kidney Failure: Answering Questions Patients Ask About Pregnancy.Kidney international reports · 2022Review
- Acute kidney injury during pregnancy in kidney transplant recipients.Clinical transplantation · 2022Review
- Pregnancy in Renal Transplant Recipients: Histopathology Provides New Insight.Kidney international reports · 2022Article
Corrections and comments
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Authors and funding
9 authors at 4 institutions in 1 country.
Funding
Abstract
introductionWomen with advanced kidney disease are advised to wait until after transplant to pursue pregnancy, but the impact of pregnancy on estimated glomerular filtration rate (eGFR) decline and kidney histology is unclear.
methodsWe identified a cohort of women aged 18 to 44 years at transplant from 1996 to 2014 at our 3-site program (
resultsThere were 37 women with one or more pregnancies lasting longer than 20 weeks gestation post-transplant. Comparing women with and without pregnancy post-transplant, there was a significant increase in the rate of eGFR decline after pregnancy (-2.4 ml/min per 1.73 m
conclusionPregnancy affects the rate of eGFR decline in the allograft. Postpregnancy biopsy findings revealed an increase in vascular injury, which could be a potential mechanism. We did not find a significant increase in risk of graft failure or reduction in eGFR by 50% owing to pregnancy.
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Registered trials
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