ArticleOsteoporosis and sarcopenia2021
Prevalence and determinants of sarcopenia in Indian patients with chronic kidney disease stage 3 & 4.
Article in Osteoporosis and sarcopenia, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 2 of them syntheses that pooled it.
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Who cites it
12 citing papers in PubMed, 2 syntheses or guidelines pooled it, 15 citations in OpenAlex.
- Prevalence and diagnostic variability of sarcopenia in India: A systematic review and meta-analysis.The Indian journal of medical research · 2026Pooled it
- Creatinine-to-cystatin C ratio as muscle assessment tool and predictive value for mortality and sarcopenia in patients with chronic kidney disease: a meta-analysis.Frontiers in nutrition · 2025Pooled it
- Association of low calf circumference and underweight with sarcopenia in older adults with chronic kidney disease: a cross-sectional study.Renal failure · 2026Article
- Balance in children with chronic kidney disease: the relationship between skeletal muscle mass index, fatigue, and physical function.Pediatric nephrology (Berlin, Germany) · 2025Article
- An Indian Consensus on Sarcopenia: Epidemiology, Etiology, Clinical Impact, Screening, and Therapeutic Approaches.International journal of general medicine · 2025Article
- Addition of bioimpedance-derived body cell mass improves performance of serum creatinine-based GFR estimation in a chronic kidney disease cohort.International urology and nephrology · 2024Article
- Changes in body composition in relation to estimated glomerular filtration rate and physical activity in predialysis chronic kidney disease.Chronic diseases and translational medicine · 2022Article
- Ultrasound for thigh muscle thickness is a valuable tool in the diagnosis of sarcopenia in Indian patients with predialysis chronic kidney disease.Osteoporosis and sarcopenia · 2022Article
- Potential implications of blood flow restriction exercise on patients with chronic kidney disease: a brief review.Journal of exercise rehabilitation · 2022Review
- Recognizing the importance of physical activity on sarcopenia in chronic kidney disease - Reply.Osteoporosis and sarcopenia · 2022Article
- Recognizing the importance of physical activity on sarcopenia in chronic kidney disease.Osteoporosis and sarcopenia · 2022Article
- Uremic Sarcopenia.Indian journal of nephrologyReview
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesThere is limited literature on the prevalence and determinants of sarcopenia in the Indian predialysis chronic kidney disease (CKD) population. The current study attempts to characterize sarcopenia in CKD stages 3 & 4 using 3-compartment model dual-energy X-ray absorptiometry (DXA).
methodsThis is secondary data from a randomized trial on bicarbonate supplementation for preserving muscle mass. A 3-compartment DXA was done to assess body composition in 188 subjects aged 18 to 65, with stable kidney function. Sarcopenia was defined by Asian Working Group criteria - appendicular skeletal mass index < 5.4 kg/m
resultsSarcopenia was present in 69.1% (n = 130). There was no difference in the prevalence of sarcopenia in CKD stage 3 (n = 62; 72.1%) vs CKD stage 4 (n = 68, 66.7%); P = 0.434. A lower body mass index (BMI) (OR 1.69; 95% CI 1.43, 2.01) and lower bicarbonate levels (OR 1.22; 95% CI 1.02, 1.47), and age (OR 0.95; 95% CI 0.91, 0.98) was independently associated with the muscle mass. A BMI cut-off of 18 failed to identify sarcopenia in 78.4% (n = 102) subjects (Kappa statistic 0.396). The receiver operating characteristic curve for mid-arm muscle circumference for identifying sarcopenia was 0.651 (95% CI 0.561, 0.740).
conclusionsSarcopenia is highly prevalent in CKD 3 and 4. Sarcopenic individuals are older, with a low BMI and lower bicarbonate levels. The anthropometric parameters and biochemical parameters did not help identify sarcopenia in the predialysis population.
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