Evidence map›Paper›PMID 35005024›Full record

ArticleBioMed research international2021

Improved Activation and Hemodynamic Response Function of Olfactory fMRI Using Simultaneous Multislice with Reduced TR Acquisition.

Hong Chen, Jianzhong Yin, Che He, Yalin Wu, Miaomiao Long, Guoping Liu, Hongyan Ni, Hua Jin, Yawu Liu

Open access · hybridAbstract read
In one paragraph

Article in BioMed research international, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 2 countries.

Hong ChenThe First Central Clinical College of Tianjin Medical University, Tianjin 300070, China.ORCID https://orcid.org/0000-0002-7136-7075
Jianzhong YinDepartment of Radiology, Tianjin First Central Hospital, Tianjin Medical Imaging Institution, Tianjin 300110, China.ORCID https://orcid.org/0000-0002-6821-1686
Che HeThe First Central Clinical College of Tianjin Medical University, Tianjin 300070, China.
Yalin WuThe First Central Clinical College of Tianjin Medical University, Tianjin 300070, China.
Miaomiao LongDepartment of Radiology, Tianjin First Central Hospital, Tianjin Medical Imaging Institution, Tianjin 300110, China.ORCID https://orcid.org/0000-0002-1064-8922
Guoping LiuDepartment of Neurology, Tianjin First Central Hospital, Tianjin 300110, China.
Hongyan NiDepartment of Radiology, Tianjin First Central Hospital, Tianjin Medical Imaging Institution, Tianjin 300110, China.
Hua JinFaculty of Psychology, Tianjin Normal University, Tianjin 300380, China.
Yawu LiuDepartments of Neurology and Clinical Radiology, Kuopio University Hospital, University of Eastern Finland, Kuopio 33100, Finland.
Tianjin First Center Hospital · CNTianjin Medical University · CNTianjin Normal University · CNUniversity of Eastern Finland · FI

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThe respiration could decrease the time synchronization between odor stimulation and data acquisition, consequently deteriorating the functional activation and hemodynamic response function (HRF) in olfactory functional magnetic resonance imaging (fMRI) with a conventional repetition time (TR). In this study, we aimed to investigate whether simultaneous multislice (SMS) technology with reduced TR could improve the blood oxygen level-dependent (BOLD) activation and optimize HRF modeling in olfactory fMRI.

methodsSixteen young healthy subjects with normal olfaction underwent olfactory fMRI on a 3T MRI scanner using a 64 channel head coil. FMRI data were acquired using SMS acceleration at three different TRs: 3000 ms, 1000 ms, and 500 ms. Both metrics of BOLD activation (activated voxels, mean, and maximum

resultsThe 500 ms and 1000 ms TRs both significantly improved the number of activated voxels, mean, and maximum

conclusionsThe fast image acquisition technique of SMS with reduced TR could significantly improve the functional activation and HRF curve in olfactory fMRI.

Indexed as

AdultBrain MappingEcho-Planar ImagingFemaleHemodynamicsHippocampusHumansImage Processing, Computer-AssistedMagnetic Resonance ImagingMaleOxygen SaturationSmellYoung Adult

Identifiers

PMID35005024
PMCPMC8731284
OpenAlexW4200531547

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.