Evidence map›Paper›PMID 35004920›Full record

ArticleFrontiers in veterinary science2021

Outcomes Associated With Osteochondral Allograft Transplantation in Dogs.

Samuel P Franklin, Aaron M Stoker, Sean M Murphy, Michael P Kowaleski, Mitchell Gillick, Stanley E Kim, Michael Karlin, Alan Cross, James L Cook

Erratum issuedAbstract read
In one paragraph

Article in Frontiers in veterinary science, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors.

Samuel P FranklinColorado Canine Orthopedics and Rehab, Colorado Springs, CO, United States.
Aaron M StokerThompson Laboratory for Regenerative Orthopaedics, University of Missouri, Columbia, MO, United States.
Sean M MurphyWestVet Animal Emergency and Specialty Center, Garden City, ID, United States.
Michael P KowaleskiDepartment of Clinical Sciences, Cummings School of Veterinary Medicine, Tufts University, North Grafton, MA, United States.
Mitchell GillickToronto Veterinary Emergency and Referral Hospital, Toronto, ON, Canada.
Stanley E KimDepartment of Small Animal Clinical Sciences, University of Florida, Gainesville, FL, United States.
Michael KarlinDepartment of Clinical Sciences, Cummings School of Veterinary Medicine, Tufts University, North Grafton, MA, United States.
Alan CrossBluePearl Pet Hospital, Atlanta, GA, United States.
James L CookThompson Laboratory for Regenerative Orthopaedics, University of Missouri, Columbia, MO, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The purpose of this study was to retrospectively characterize outcomes and complications associated with osteochondral allograft transplantation for treating chondral and osteochondral lesions in a group of client-owned dogs with naturally-occurring disease. Records were reviewed for information on signalment, treated joint, underlying pathology (e.g., osteochondritis dissecans; OCD), and type, size, and number of grafts used. Complications were classified as "trivial" if no treatment was provided, "non-surgical" if non-surgical treatment were needed, "minor surgical" if a minor surgical procedure such as pin removal were needed but the graft survived and function was acceptable, or "major" if the graft failed and revision surgery were needed. Outcomes were classified as unacceptable, acceptable, or full function. Thirty-five joints in 33 dogs were treated including nine stifles with lateral femoral condyle (LFC) OCD and 10 stifles with medial femoral condyle (MFC) OCD treated with osteochondral cylinders or "plugs." There were 16 "complex" procedures of the shoulder, elbow, hip, stifle, and tarsus using custom-cut grafts. In total there were eight trivial complications, one non-surgical complication, two minor surgical complications, and five major complications for a total of 16/35 cases with complications. Accordingly, there were five cases with unacceptable outcomes, all of whom had major complications while the other 30 cases had successful outcomes. Of the 30 cases with successful outcomes, 15 had full function and 15 had acceptable function. Based on these subjective outcome assessments, it appears osteochondral allograft transplantation is a viable treatment option in dogs with focal or complex cartilage defects. However, no conclusions can be made regarding the inferiority or superiority of allograft transplantation in comparison to other treatment options based upon these data.

Indexed as

allograftcartilage repairdogsosteochondralosteochondritis dissecansosteochondrosistransplants

Identifiers

PMID35004920
PMCPMC8739896

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.