Evidence map›Paper›PMID 35004870›Full record

ArticleFrontiers in cardiovascular medicine2021

(Pro)renin Receptor Inhibition Reduces Plasma Cholesterol and Triglycerides but Does Not Attenuate Atherosclerosis in Atherosclerotic Mice.

Dien Ye, Xiaofei Yang, Liwei Ren, Hong S Lu, Yuan Sun, Hui Lin, Lunbo Tan, Na Wang, Genevieve Nguyen, Michael Bader and 7 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in cardiovascular medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.4field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 8 institutions in 5 countries.

Dien YeDepartment of Pharmacology, College of Pharmacy, Shenzhen Technology University, Shenzhen, China.
Xiaofei YangTranslational Medicine Collaborative Innovation Center, The Second Clinical Medical College (Shenzhen People's Hospital) of Jinan University, Shenzhen, China.
Liwei RenDepartment of Pharmacology, College of Pharmacy, Shenzhen Technology University, Shenzhen, China.
Hong S LuSaha Cardiovascular Research Center and Department of Physiology, University of Kentucky, Lexington, KY, United States.
Yuan SunDepartment of Pharmacology, College of Pharmacy, Shenzhen Technology University, Shenzhen, China.
Hui LinDepartment of Pharmacology, College of Pharmacy, Shenzhen Technology University, Shenzhen, China.
Lunbo TanDepartment of Pharmacology, College of Pharmacy, Shenzhen Technology University, Shenzhen, China.
Na WangDepartment of Pharmacology, College of Pharmacy, Shenzhen Technology University, Shenzhen, China.
Genevieve NguyenInstitut National de la Santé et de la Recherche Médicale (INSERM) and Collège de France Early Development and Pathologies Center for Interdisciplinary Research in Biology and Experimental Medicine Unit, Paris, France.
Michael BaderMax-Delbrück Center for Molecular Medicine (MDC), Berlin, Germany.
Adam E MullickIonis Pharmaceuticals, Inc, Carlsbad, CA, United States.
A H Jan DanserDivision of Pharmacology and Vascular Medicine, Department of Internal Medicine, Erasmus Medical Center, Rotterdam University, Rotterdam, Netherlands.
Alan DaughertySaha Cardiovascular Research Center and Department of Physiology, University of Kentucky, Lexington, KY, United States.
Yizhou JiangInstitute for Advanced Study, Shenzhen University, Shenzhen, China.
Yidan SunDepartment of Physiology, Shenzhen University Health Science Center, Shenzhen University, Shenzhen, China.
Furong LiTranslational Medicine Collaborative Innovation Center, The Second Clinical Medical College (Shenzhen People's Hospital) of Jinan University, Shenzhen, China.
Xifeng LuDepartment of Pharmacology, College of Pharmacy, Shenzhen Technology University, Shenzhen, China.
Shenzhen Technology University · CNErasmus MC · NLJinan University · CNUniversity of Kentucky · USCentre Interdisciplinaire de Recherche en Biologie · FRIonis Pharmaceuticals (United States) · USMax Delbrück Center · DEShenzhen University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

cholesterolmacrophage(Pro)renin receptor (PRR)renin- angiotensin systemV-ATPase = vacuolar H+-adenosine triphosphatase

Identifiers

PMID35004870
PMCPMC8739895
OpenAlexW4200004801

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.