Evidence map›Paper›PMID 35004774›Full record

ArticleFrontiers in medicine2021

Siderophore-Mediated Iron Acquisition Plays a Critical Role in Biofilm Formation and Survival of

Fernando Oliveira, Tânia Lima, Alexandra Correia, Ana Margarida Silva, Cristina Soares, Simone Morais, Samira Weißelberg, Manuel Vilanova, Holger Rohde, Nuno Cerca

Open access · goldAbstract read
In one paragraph

Article in Frontiers in medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
0.7field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 21 citations in OpenAlex.

  1. Article
  2. Article
  3. Research Progress on perinatalFrontiers in microbiology · 2026
    Review
  4. Review
  5. Article
  6. Article
  7. Halogenated quinoline kill agent rapidly induces iron starvation ofMedicinal chemistry research : an international journal for rapid communications on design and mechanisms of action of biologically active agents · 2025
    Article
  8. Article
  9. Article
  10. Review
  11. Targeting Siderophore Biosynthesis to Thwart Microbial Growth.International journal of molecular sciences · 2025
    Review
  12. Article
  13. Non-classical roles of bacterial siderophores in pathogenesis.Frontiers in cellular and infection microbiology · 2024
    Review
  14. Antibacterial MccM as the Major Microcin inInternational journal of molecular sciences · 2023
    Article
  15. Involvement of the Iron-Regulated LociMicrobiology spectrum · 2022
    Article
  16. FightingFrontiers in cellular and infection microbiology · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 2 countries.

Fernando OliveiraLIBRO - Laboratory of Research in Biofilms Rosário Oliveira, Centre of Biological Engineering, University of Minho, Braga, Portugal.
Tânia Limai3S - Instituto de Investigação e Inovação em Saúde, Universidade do Porto, Porto, Portugal.
Alexandra Correiai3S - Instituto de Investigação e Inovação em Saúde, Universidade do Porto, Porto, Portugal.
Ana Margarida Silvai3S - Instituto de Investigação e Inovação em Saúde, Universidade do Porto, Porto, Portugal.
Cristina SoaresREQUIMTE-LAQV, Instituto Superior de Engenharia do Porto, Instituto Politécnico do Porto, Porto, Portugal.
Simone MoraisREQUIMTE-LAQV, Instituto Superior de Engenharia do Porto, Instituto Politécnico do Porto, Porto, Portugal.
Samira WeißelbergInstitut für Medizinische Mikrobiologie, Virologie und Hygiene, Universitätsklinikum Hamburg-Eppendorf, Hamburg, Germany.
Manuel Vilanovai3S - Instituto de Investigação e Inovação em Saúde, Universidade do Porto, Porto, Portugal.
Holger RohdeInstitut für Medizinische Mikrobiologie, Virologie und Hygiene, Universitätsklinikum Hamburg-Eppendorf, Hamburg, Germany.
Nuno CercaLIBRO - Laboratory of Research in Biofilms Rosário Oliveira, Centre of Biological Engineering, University of Minho, Braga, Portugal.
i3S - Instituto de Investigação e Inovação em Saúde, Universidade do Porto · PTPolytechnic Institute of Porto · PTUniversity Medical Center Hamburg-Eppendorf · DEUniversity of Minho · PT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Iron acquisition through siderophores, a class of small, potent iron-chelating organic molecules, is a widely spread strategy among pathogens to survive in the iron-restricted environment found in the host. Although these molecules have been implicated in the pathogenesis of several species, there is currently no comprehensive study addressing siderophore production in

Indexed as

biofilmsironmutagenesissiderophoresStaphylococcus epidermidisvirulence

Identifiers

PMID35004774
PMCPMC8738164
OpenAlexW4200584589

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.