Evidence map›Paper›PMID 35004753›Full record

ArticleFrontiers in medicine2021

Axl Is Essential for

Wenyi Wu, Huizuo Xu, Zhishang Meng, Jianxi Zhu, Siqi Xiong, Xiaobo Xia, Hetian Lei

Erratum issuedOpen access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.7field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
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  4. Review
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  6. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Wenyi WuDepartment of Ophthalmology, National Clinical Research Center for Geriatric Disorders, Xiangya Hospital of Central South University, Changsha, China.
Huizuo XuDepartment of Ophthalmology, National Clinical Research Center for Geriatric Disorders, Xiangya Hospital of Central South University, Changsha, China.
Zhishang MengDepartment of Ophthalmology, The Second Xiangya Hospital of Central South University, Changsha, China.
Jianxi ZhuDepartment of Orthopedics, Xiangya Hospital of Central South University, Changsha, China.
Siqi XiongDepartment of Ophthalmology, National Clinical Research Center for Geriatric Disorders, Xiangya Hospital of Central South University, Changsha, China.
Xiaobo XiaDepartment of Ophthalmology, National Clinical Research Center for Geriatric Disorders, Xiangya Hospital of Central South University, Changsha, China.
Hetian LeiDepartment of Ophthalmology, Shenzhen Eye Institute, Shenzhen Eye Hospital, Jinan University, Shenzhen, China.
Central South University · CNHunan University · CNJinan University · CNXiangya Hospital Central South University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Proliferative diabetic retinopathy (PDR), characterized mainly with abnormal epiretinal angiogenesis forming fibrovascular membranes (FVMs), threatens vision of people with diabetes; FVMs consist of extracellular matrix and a variety of cell types including vascular endothelial cells. Axl, one of receptor tyrosine kinases, can be activated indirectly by vascular endothelial growth factor-A (VEGF-A)

Indexed as

AxlCRISPR/Cas9GAS6HRECsPDR vitreousR428

Identifiers

PMID35004753
PMCPMC8734562
OpenAlexW4200255113

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.