Evidence map›Paper›PMID 35004670›Full record

ArticleFrontiers in cell and developmental biology2021

Effect of Sperm Cryopreservation on miRNA Expression and Early Embryonic Development.

Xiaoyu Xu, Wanqiong Li, Lina Zhang, Yazhong Ji, Jiaying Qin, Lu Wang, Mingwen Wang, Lingbin Qi, Jinfeng Xue, Bo Lv and 2 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cell and developmental biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
4.6field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 25 citations in OpenAlex.

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  17. Cellular and Molecular Nature of Fragmentation of Human Embryos.International journal of molecular sciences · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Xiaoyu XuDepartment of Regenerative Medicine, Tongji University School of Medicine, Shanghai, China.
Wanqiong LiReproductive Medicine Center, Tongji Hospital, Tongji University School of Medicine, Shanghai, China.
Lina ZhangReproductive Medicine Center, Tongji Hospital, Tongji University School of Medicine, Shanghai, China.
Yazhong JiReproductive Medicine Center, Tongji Hospital, Tongji University School of Medicine, Shanghai, China.
Jiaying QinDepartment of Regenerative Medicine, Tongji University School of Medicine, Shanghai, China.
Lu WangDepartment of Regenerative Medicine, Tongji University School of Medicine, Shanghai, China.
Mingwen WangDepartment of Regenerative Medicine, Tongji University School of Medicine, Shanghai, China.
Lingbin QiDepartment of Regenerative Medicine, Tongji University School of Medicine, Shanghai, China.
Jinfeng XueDepartment of Regenerative Medicine, Tongji University School of Medicine, Shanghai, China.
Bo LvDepartment of Regenerative Medicine, Tongji University School of Medicine, Shanghai, China.
Xunyi ZhangReproductive Medicine Center, Tongji Hospital, Tongji University School of Medicine, Shanghai, China.
Zhigang XueDepartment of Regenerative Medicine, Tongji University School of Medicine, Shanghai, China.
Tongji University · CNTongji Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Although sperm preservation is a common means of personal fertility preservation, its effects on embryonic development potential need further investigation. The purpose of this study was to identify key microRNA (miRNA) in cryopreserved sperm and determine the changes of these miRNAs and their target genes during embryonic development using cryopreserved sperm. Moreover, the embryonic development potential of cryopreserved sperm was estimated in assisted reproductive technology (ART), where key miRNAs and target genes were validated in sperm and subsequent embryos. Clinical data of embryonic development from cryopreserved sperm indicated a significant decrease in fertilization rate in both

Indexed as

embryonic developmentgamete cryopreservationmiR-148b-3pmiRNA expressionsperm cryopreservation

Identifiers

PMID35004670
PMCPMC8728010
OpenAlexW4200258220

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.