Evidence map›Paper›PMID 35004657›Full record

ArticleFrontiers in bioengineering and biotechnology2021

Genipin Cross-Linked Decellularized Nucleus Pulposus Hydrogel-Like Cell Delivery System Induces Differentiation of ADSCs and Retards Intervertebral Disc Degeneration.

Lei Yu, Yi Liu, Jianxin Wu, Shuang Wang, Jiangming Yu, Weiheng Wang, Xiaojian Ye

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in bioengineering and biotechnology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
3.3field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 32 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Lei YuDepartment of Orthopedics, Second Affiliated Hospital of Naval Medical University, Shanghai, China.
Yi LiuDepartment of Orthopedics, Second Affiliated Hospital of Naval Medical University, Shanghai, China.
Jianxin WuDepartment of Orthopedics, First Affiliated Hospital of Naval Medical University, Shanghai, China.
Shuang WangDepartment of Orthopedics, Second Affiliated Hospital of Naval Medical University, Shanghai, China.
Jiangming YuDepartment of Orthopaedics, Tongren Hospital, Shanghai Jiaotong University, Shanghai, China.
Weiheng WangDepartment of Orthopedics, Second Affiliated Hospital of Naval Medical University, Shanghai, China.
Xiaojian YeDepartment of Orthopaedics, Tongren Hospital, Shanghai Jiaotong University, Shanghai, China.
Second Military Medical University · CNTongren Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Intervertebral disc degeneration (IDD) is the pathological basis of disc degenerative diseases (DDD). Reduction in the number of cells and degeneration of the extracellular matrix (ECM) in the nucleus pulposus (NP) are characteristics of IDD. Bio-hydrogel combined with stem cell transplantation is a promising treatment. Injectable ECM hydrogels have good biological activity and

Indexed as

ADSCgenipinintervertebral disc degenerationnucleus pulposustissue engineering

Identifiers

PMID35004657
PMCPMC8733700
OpenAlexW4200464287

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.