Evidence map›Paper›PMID 35004294›Full record

ArticleFrontiers in oncology2021

Diagnostic Value of Radiomics Analysis in Contrast-Enhanced Spectral Mammography for Identifying Triple-Negative Breast Cancer.

Yongxia Zhang, Fengjie Liu, Han Zhang, Heng Ma, Jian Sun, Ran Zhang, Lei Song, Hao Shi

Open access · goldAbstract read
In one paragraph

Article in Frontiers in oncology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 3 pooled it
0.7field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 3 syntheses or guidelines pooled it, 13 citations in OpenAlex.

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  5. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Yongxia ZhangDepartment of Medical Imaging, Shandong Qianfoshan Hospital, Cheeloo College of Medicine, Shandong University, Jinan, China.
Fengjie LiuDepartment of Radiology, Yantai Yuhuangding Hospital, Yantai, China.
Han ZhangDepartment of Radiology, Yantai Yuhuangding Hospital, Yantai, China.
Heng MaDepartment of Radiology, Yantai Yuhuangding Hospital, Yantai, China.
Jian SunDepartment of Radiology, Yantai Yuhuangding Hospital, Yantai, China.
Ran ZhangMarketing Research Department, Huiying Medical Technology Co. Ltd, Beijing, China.
Lei SongDepartment of Geratology, Yantai Yuhuangding Hospital, Yantai, China.
Hao ShiDepartment of Medical Imaging, Shandong Qianfoshan Hospital, Cheeloo College of Medicine, Shandong University, Jinan, China.
Yuhuangding Hospital · CNShandong Provincial QianFoShan Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo evaluate the value of radiomics analysis in contrast-enhanced spectral mammography (CESM) for the identification of triple-negative breast cancer (TNBC).

methodCESM images of 367 pathologically confirmed breast cancer patients (training set: 218, testing set: 149) were retrospectively analyzed. Cranial caudal (CC), mediolateral oblique (MLO), and combined models were built on the basis of the features extracted from subtracted images on CC, MLO, and the combination of CC and MLO, respectively, in the tumour region. The performance of the models was evaluated through receiver operating characteristic (ROC) curve analysis, the Hosmer-Lemeshow test, and decision curve analysis (DCA). The areas under ROC curves (AUCs) were compared through the DeLong test.

resultsThe combined CC and MLO model had the best AUC and sensitivity of 0.90 (95% confidence interval: 0.85-0.96) and 0.97, respectively. The Hosmer-Lemeshow test yielded a non-significant statistic with

conclusionsMachine learning models based on subtracted images in CESM images were valuable for distinguishing TNBC and NTNBC. The model with the combined CC and MLO features had the best performance compared with models that used CC or MLO features alone.

Indexed as

breast cancercontrast-enhanced spectral mammographymolecular subtypesradiomicstriple-negative breast cancer

Identifiers

PMID35004294
PMCPMC8733550
OpenAlexW4200067858

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.