Evidence map›Paper›PMID 35004017›Full record

ArticleCureus2021

Response of Pediatric Choroidal Neovascularization to Anti-Vascular Endothelial Growth Factor.

Sunil Ruparelia, Aishwarya Sundaram, Mishari Dahrab, Chris Symonds, Alan Cruess

Open access · diamondAbstract readCase Reports
In one paragraph

Article in Cureus, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Sunil RupareliaDepartment of Ophthalmology, Faculty of Medicine, Dalhousie University, Halifax, CAN.
Aishwarya SundaramDepartment of Ophthalmology, Faculty of Medicine, Dalhousie University, Halifax, CAN.
Mishari DahrabDepartment of Ophthalmology, Izaak Walton Killam Health Center, Halifax, CAN.
Chris SymondsDepartment of Ophthalmology, Saint John Regional Hospital, Saint John, CAN.
Alan CruessDepartment of Ophthalmology, Faculty of Medicine, Dalhousie University, Halifax, CAN.
Dalhousie University · CASaint John Regional Hospital · CAIzaak Walton Killam Health Centre · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Choroidal neovascularization (CNV) is a rare condition in children but poses a substantial threat to vision. Anti-vascular endothelial growth factor (anti-VEGF) therapy is commonly used in the pediatric population to treat retinopathy of prematurity. However, the use of anti-VEGF is less common for childhood CNV due to the rarity of CNV in the pediatric population. We report the case of a 10-year-old male presenting with an idiopathic choroidal neovascular membrane. Following a relapse of subretinal fluid after photodynamic therapy, anti-VEGF (bevacizumab) was injected and resulted in remission of the neovascular membrane and improved visual outcome. Further studies are required to elucidate the long-term outcomes associated with the use of anti-VEGF in pediatric patients.

Indexed as

anti-vegfchoroidal neovascular membraneophthalmologypediatric ophthalmologyretina

Identifiers

PMID35004017
PMCPMC8727322
OpenAlexW4200537896

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.