ReviewCureus2021
Coronary Artery Calcium Score - A Reliable Indicator of Coronary Artery Disease?
Review in Cureus, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
35 citing papers in PubMed, 1 synthesis or guideline pooled it, 51 citations in OpenAlex.
- Comparison of photon-counting CT angiography with energy-integrating CT angiography in coronary artery stenosis: a systematic review and meta-analysis.BMC medical imaging · 2025Pooled it
- Detection of obstructive coronary artery disease using a deep learning and machine learning ensemble: a retrospective feasibility study.European heart journal. Digital health · 2026Article
- Age- and Sex-Related Patterns in Coronary CT Angiography Referrals and Coronary Atherosclerotic Burden: A Single-Center Real-World Referral-Based Analysis.Medicina (Kaunas, Lithuania) · 2026Article
- Risk prediction and prevention in patients with advanced subclinical atherosclerosis.BMC cardiovascular disorders · 2026Review
- Association of coronary artery calcium and carotid intima-media thickness with white matter hyperintensity.Medicine · 2026Article
- Metabolic syndrome and high-sensitivity C-reactive protein co-modify the risk of coronary artery calcification.Frontiers in cardiovascular medicine · 2026Article
- Sodium Intake and Its Relation to Coronary Calcium Score in Relatively Young Korean Adults.Global heart · 2026Article
- Interplay of menopause, coronary artery calcium score and cardiovascular disease risk.World journal of cardiology · 2025Article
- Role of Coronary Artery Calcium Score CT in Risk Stratification of Asymptomatic Individuals.Journal of cardiovascular development and disease · 2025Review
- Phthalate exposure is associated with subclinical coronary atherosclerosis: The Aragon Workers' Health Study (AWHS).American journal of preventive cardiology · 2025Article
- Relationship between the prevalence of breast arterial calcifications on mammography and coronary calcifications on Chest CT: A cross-sectional study.Saudi medical journal · 2025Article
- Evaluating the generalizability of an automated coronary artery calcium segmentation and scoring algorithm using multi-vendor dataset.Scientific reports · 2025Article
- Review
- Considerations on the Development of Therapeutics in Vascular Calcification.Journal of cardiovascular development and disease · 2025Review
- Coronary Calcium Scoring Using True and Virtual Non-Contrast Reconstructions on Photon-Counting CT with Differing Slice Increment: Impact on Calcium Severity Classifications.Journal of clinical medicine · 2025Article
- Vascular dysfunction is associated with major adverse cardiovascular events in prediabetes: A cohort study.PloS one · 2025Observational
- Understanding Vascular Calcification in Chronic Kidney Disease: Pathogenesis and Therapeutic Implications.International journal of molecular sciences · 2024Review
- The role of cardiac adipose tissue in coronary artery disease: a narrative review of cardiac imaging studies.Quantitative imaging in medicine and surgery · 2024Review
- Differential Association of COPD Subtypes With Cardiovascular Events and COPD Exacerbations.Chest · 2024Article
- Impact of tooth loss and patient characteristics on coronary artery calcium score classification and prediction.Scientific reports · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 7 institutions in 5 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Coronary artery disease (CAD) is caused by atheromatous blockage of coronary vessels leading to acute coronary events that usually occur when a plaque ruptures and a thrombus forms. CAD is a known cause of significant cardiovascular events, accounting for more than 50% of the deaths in western countries, and most of the patients with CAD remain asymptomatic. The coronary artery calcium (CAC) score has been created as a measure of coronary atherosclerosis. This article has compiled various studies that conclude the clinical relationship between coronary artery calcium and the development of cardiovascular (CV) events by using the CAC score as a reliable indicator of CAD. This article has reviewed the pathophysiology and risk factors of CAD, along with various methods of CAC scoring. It also underlined the reliability of CAC scoring for early detection of CAD in asymptomatic individuals. We emphasized the importance of age-dependent risk factor analysis combined with practical screening tools like CAC scoring for early diagnosis of CAD can help direct the treatment and prevent deaths in asymptomatic individuals.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.