ReviewJournal of ophthalmology2021
Comparison of Patient Outcomes following Implantation of Trifocal and Extended Depth of Focus Intraocular Lenses: A Systematic Review and Meta-Analysis.
Review in Journal of ophthalmology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 3 syntheses or guidelines pooled it, 26 citations in OpenAlex.
- Visual Outcomes After Mix-and-Match Implantation of Trifocal and Extended Depth-of-Focus Intraocular Lenses: A Systematic Review and Meta-Analysis.Medicina (Kaunas, Lithuania) · 2026Pooled it
- Trifocal versus extended depth of focus (EDOF) intraocular lenses after cataract extraction.The Cochrane database of systematic reviews · 2024Pooled it
- Comparative efficacy and safety of all kinds of intraocular lenses in presbyopia-correcting cataract surgery: a systematic review and meta-analysis.BMC ophthalmology · 2024Pooled it
- Presbyopia: Current Perspectives and Prospects for Patients.Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists) · 2026Review
- Intermediate Visual Performance of Clareon Versus Eyhance Enhanced Monofocal Intraocular Lenses.Diagnostics (Basel, Switzerland) · 2026Article
- A comparative study of extended depth of focus, bifocal intraocular lenses and their mix-and-match.International journal of ophthalmology · 2026Article
- Outcomes of Extended Monofocal and Extended Depth of Focus Intraocular Lens Implantation by a Trainee Surgeon in an Australian Tertiary Public Hospital.Clinical ophthalmology (Auckland, N.Z.) · 2026Article
- Comparison of visual outcomes between bilateral EDOF IOL implantation and combined EDOF and bifocal IOL implantation.International journal of ophthalmology · 2026Article
- Using Large Language Models for In Silico Development and Simulation of a Patient-Reported Outcome Questionnaire for Cataract Surgery with Various Intraocular Lenses: A Pre-Validation Study.Journal of clinical medicine · 2025Article
- Visual Performance After Bilateral Implantation of a New Enhanced Monofocal Hydrophobic Acrylic Intraocular Lens Targeted for Mini-Monovision.Life (Basel, Switzerland) · 2025Article
- Visual outcomes with a non-diffractive enhanced depth-of-focus IOL in patients with age-related macular degeneration.Frontiers in medicine · 2025Article
- Clinical Outcomes of Enhanced Monofocal (Mono-EDOF) Intraocular Lenses with the Mini-Monovision Technique versus Trifocal Intraocular Lenses: A Comparative StudyTurkish journal of ophthalmology · 2024Observational
- [Corneal wound healing-Pharmacological treatment].Die Ophthalmologie · 2024Article
- Comparative Evaluation of Visual Performance and Patient Satisfaction following Cataract Surgery: A Retrospective Analysis of an Extended Depth-of-Focus Intraocular Lens and a Diffractive Multifocal Lens with Extended Depth of Focus.Journal of clinical medicine · 2023Article
- Premium Intraocular Lenses in Glaucoma-A Systematic Review.Bioengineering (Basel, Switzerland) · 2023Review
- A tapt1 knock-out zebrafish line with aberrant lens development and impaired vision models human early-onset cataract.Human genetics · 2023Article
- Head-to-Head Comparison of Intermediate Vision of Two Monofocal Intraocular Lenses.Clinical ophthalmology (Auckland, N.Z.) · 2023Article
- Dysphotopsias or Unwanted Visual Phenomena after Cataract Surgery.Life (Basel, Switzerland) · 2022Review
- Depth of field and visual performance after implantation of a new hydrophobic trifocal intraocular lens.BMC ophthalmology · 2022Observational
- When trifocal IOLs disappoint: diagnostic and management pathway.Therapeutic advances in ophthalmologyReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThe purpose is to compare the outcomes of implantation of trifocal intraocular lenses (TIOLs) and extended depth of focus (EDOF) intraocular lenses (IOLs).
methodsA comprehensive search of PubMed, Cochrane Library, EMBASE, and ClinicalTrial.gov was conducted in March 2020 to identify relevant studies. A meta-analysis of the results was performed. Patients implanted with EDOF IOLs or TIOLs in previous studies were included. The primary outcomes of the study were uncorrected distance visual acuity (UDVA), uncorrected intermediate visual acuity (UIVA), uncorrected near visual acuity (UNVA), and defocus curve.
resultsTIOLs and EDOF IOLs provided comparable binocular UDVA (MD = -0.01, 95% CI: -0.04, 0.03, logMAR). However, EDOF IOLs provided better UIVA (MD: -0.08, 95% CI: -0.14, -0.01, logMAR) and worse UNVA (MD: 0.10, 95% CI: 0.06, 0.14, logMAR) than TIOLs. Fewer patients achieved spectacle independence after implantation of EDOF IOLs (RR: 0.74, 95% CI: 0.63, 0.87) than after implantation of TIOLs, especially for near vision (RR = 0.82, 95% CI: 0.68, 0.99). There was no statistically significant difference in contrast sensitivity (CS) under photopic or mesopic conditions with both IOLs. Patient satisfaction after implantation of both IOLs was high.
conclusionEDOF IOLs and TIOLs provide comparable distance vision. However, EDOF IOLs provide better intermediate vision and worse near vision than TIOLs. The advantages of EDOF IOLs over TIOLs in terms of CS, aberrations, and visual disturbance are not significant. Patients are satisfied with both types of IOLs.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.