Evidence map›Paper›PMID 35003710›Full record

ArticleJournal of global health2021

Implementing community-based human papillomavirus self-sampling with SMS text follow-up for cervical cancer screening in rural, southwestern Uganda.

Naima T Joseph, Alexcer Namuli, Bernard Kakuhikire, Charles Baguma, Mercy Juliet, Patience Ayebare, Phionah Ahereza, Alexander C Tsai, Mark J Siedner, Thomas R Randall and 2 more

Open access · goldAbstract read
In one paragraph

Article in Journal of global health, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 16 citations in OpenAlex.

  1. Trial
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Review
  15. Review
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 5 institutions in 2 countries.

Naima T JosephDepartment of Obstetrics and Gynecology, Beth Isreal Deaconness Medical Center, Boston, MA, USA.
Alexcer NamuliDepartment of Obstetrics & Gynecology, Mbarara Regional Referral Hospital, Mbarara, Uganda.
Bernard KakuhikireMbarara University of Science and Technology, Mbarara, Uganda.
Charles BagumaMbarara University of Science and Technology, Mbarara, Uganda.
Mercy JulietMbarara University of Science and Technology, Mbarara, Uganda.
Patience AyebareMbarara University of Science and Technology, Mbarara, Uganda.
Phionah AherezaMbarara University of Science and Technology, Mbarara, Uganda.
Alexander C TsaiHarvard Medical School, Boston, MA, USA.
Mark J SiednerHarvard Medical School, Boston, MA, USA.
Thomas R RandallHarvard Medical School, Boston, MA, USA.
Joseph NgonziDepartment of Obstetrics & Gynecology, Mbarara Regional Referral Hospital, Mbarara, Uganda.
Adeline A BoatinHarvard Medical School, Boston, MA, USA.
Mbarara University of Science and Technology · UGCenter for Global Health · USHarvard University · USMassachusetts General Hospital · USMbarara National Referral Hospital · UG

Funding

Social Networks, HIV Stigma, and the HIV Care Cascade in Rural UgandaR01MH113494 · NIMH · MASSACHUSETTS GENERAL HOSPITAL · PI TSAI, ALEXANDER C · 2017 to 2021
$3.2M
Wireless Physiologic Monitoring in Postpartum Women in rural UgandaK23HD097300 · NICHD · MASSACHUSETTS GENERAL HOSPITAL · PI BOATIN, ADELINE ADWOA · 2018 to 2022
$863k
NICHD NIH HHS K23 HD097300NIMH NIH HHS R01 MH113494
6 · The paper itself

Abstract

backgroundSelf-collected HPV screening may improve cervical cancer screening coverage in low resource countries, yet data guiding implementation and follow-up of abnormal results are sparse.

methodsThis is a prospective cohort implementation study of HPV self-testing program in Mbarara, Uganda with mobile phones to facilitate result notification and referral for treatment at a regional hospital. The effectiveness of the interventions was analyzed using Proctor's model of implementation. Women were interviewed following screening and at 6 months to assess acceptability and barriers to follow-up. Data were analyzed using descriptive statistics.

results159 of 194 (82%) of eligible women underwent HPV self-sampling; of these, 27 (17%) returned positive for high-risk HPV subtypes. We sent SMS messages providing test results and follow-up instructions to all participants. Seventeen (63%) hrHPV-positive participants reported receiving SMS text instructions for follow-up, of whom 6 (35%) presented for follow-up. The most common reasons for not returning were: lack of transportation (n = 11), disbelief of results (n = 5), lack of childcare (n = 4), and lack of symptoms (n = 3). Confidence in test results was higher for self-screening compared to VIA (Likert score 4.8 vs 4.4,

conclusionsDespite the use of SMS text-based referrals, only one-third of women presented for clinical follow-up after abnormal HPV testing.

Indexed as

AlphapapillomavirusPapillomavirus InfectionsUterine Cervical NeoplasmsEarly Detection of CancerFemaleFollow-Up StudiesHumansPapillomaviridaeProspective StudiesUganda

Identifiers

PMID35003710
PMCPMC8709902
OpenAlexW4200492195

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.