Evidence map›Paper›PMID 35003393›Full record

SynthesisDisease markers2021

Intraoperative Use of Topical Retropharyngeal Steroids for Dysphagia after Anterior Cervical Fusion: A Systematic Review and Meta-Analysis.

Hang Yu, Hui Dong, Binjia Ruan, Xiaohang Xu, Yongxiang Wang

Open access · hybridAbstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in Disease markers, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.0field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Hang YuClinical Medical College of Yangzhou University, Yangzhou, China.ORCID https://orcid.org/0000-0002-1544-0506
Hui DongNorthern Jiangsu People's Hospital Affiliated to Yangzhou University, Yangzhou, China.ORCID https://orcid.org/0000-0002-2890-0794
Binjia RuanNorthern Jiangsu People's Hospital Affiliated to Yangzhou University, Yangzhou, China.ORCID https://orcid.org/0000-0001-6387-5320
Xiaohang XuClinical Medical College of Yangzhou University, Yangzhou, China.ORCID https://orcid.org/0000-0002-3391-4701
Yongxiang WangNorthern Jiangsu People's Hospital Affiliated to Yangzhou University, Yangzhou, China.ORCID https://orcid.org/0000-0003-3763-7411
Northern Jiangsu People's Hospital · CNDalian Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe anterior cervical approach is commonly used clinically for cervical spondylosis, but it also results in frequent postoperative dysphagia, which can increase the risk of complications and poor treatment satisfaction in severe cases. Intraoperative local application of retropharyngeal steroids has an impact on reducing the occurrence and severity of dysphagia; however, the results of current studies vary. The meta-analysis of this randomized trial was to evaluate the effectiveness and safety of intraoperative topical retropharyngeal steroids for the control of dysphagia after anterior cervical spine surgery.

methodsTwo authors searched electronic databases such as PubMed, MEDLINE, EMBASE, Cochrane Library, and Google Scholar, respectively. The search terms were "Dysphagia," "Steroids," "Anterior Cervical Discectomy and Fusion," etc. A random effects model was used to conduct a meta-analysis based on deviance information criteria.

resultsA total of 8 studies were included in this meta-analysis after screening of 792 studies. Bazaz scores were not significantly different in the steroid group at one day postoperatively (

conclusionPerioperative local retropharyngeal steroid administration as an adjunct to anterior cervical spine surgery reduces the incidence and severity of dysphagia compared with placebo control. However, future high-quality randomized controlled studies could incorporate nonsubjective dysphagia measures and long-term follow-up on the occurrence of associated complications or other side effects.

Indexed as

Intraoperative CareAdministration, TopicalCervical VertebraeDeglutition DisordersGlucocorticoidsHumansPharynxPostoperative ComplicationsSpinal FusionGlucocorticoids

Identifiers

PMID35003393
PMCPMC8741348
OpenAlexW4206316034

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.