Evidence map›Paper›PMID 35003392›Full record

ArticleDisease markers2021

Prognostic Significance of the Combined Score of Plasma Fibrinogen and Neutrophil-Lymphocyte Ratio in Patients with Spontaneous Intracerebral Hemorrhage.

Wanchun Yang, Yunbo Yuan, Junhong Li, Yuli Shuai, Xiang Liao, Zhiyuan Yu, Hao Li, Jun Zheng

Abstract read
In one paragraph

Article in Disease markers, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
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  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Wanchun YangDepartment of Neurosurgery, West China Hospital of Sichuan University, Chengdu, 610041 Sichuan Province, China.
Yunbo YuanDepartment of Neurosurgery, West China Hospital of Sichuan University, Chengdu, 610041 Sichuan Province, China.
Junhong LiDepartment of Neurosurgery, West China Hospital of Sichuan University, Chengdu, 610041 Sichuan Province, China.
Yuli ShuaiWest China School of Medicine, Sichuan University, Chengdu, 610041 Sichuan Province, China.
Xiang LiaoDepartment of Cardiology, PLA Rocket Force Characteristic Medical Center, Beijing 100088, China.
Zhiyuan YuDepartment of Neurosurgery, West China Hospital of Sichuan University, Chengdu, 610041 Sichuan Province, China.
Hao LiDepartment of Neurosurgery, West China Hospital of Sichuan University, Chengdu, 610041 Sichuan Province, China.
Jun ZhengDepartment of Neurosurgery, West China Hospital of Sichuan University, Chengdu, 610041 Sichuan Province, China.ORCID https://orcid.org/0000-0002-1471-4747

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe combination of plasma fibrinogen and neutrophil to lymphocyte ratio (F-NLR) score is a novel inflammatory marker constituted by peripheral blood fibrinogen concentration and neutrophil to lymphocyte ratio. In the current study, we aim to explore the relationship between admission F-NLR score and intracerebral hemorrhage (ICH) and assess its prognostic predictive ability in ICH patients.

methodsThe original cohort was consecutively recruited from August 2014 to September 2017, and the validation cohort was consecutively recruited between October 2018 and March 2020. The primary outcomes were 3-month functional outcome and 1-month mortality. All statistical analyses were performed using SPSS and R software.

resultsA total of 431 and 251 ICH patients were included in original cohort and validation cohort, respectively. In the original cohort, F-NLR score could independently predict the 3-month functional outcome (adjusted OR 2.013, 95% CI 1.316-3.078,

conclusionF-NLR score was an independent indicator for both the 3-month functional outcome and 1-month mortality, and its prognostic predictive ability was superior to fibrinogen and NLR in both the original and the validation cohort.

Indexed as

LymphocytesNeutrophilsAgedCerebral HemorrhageFemaleFibrinogenHumansLeukocyte CountMaleMiddle AgedPrognosisRetrospective StudiesFibrinogen

Identifiers

PMID35003392
PMCPMC8731292

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.