Evidence map›Paper›PMID 35003306›Full record

ArticleEvidence-based complementary and alternative medicine : eCAM2021

Quercetin Relieves the Excised Great Saphenous Vein Oxidative Damage and Inflammatory Reaction.

Yunpeng Bai, Qingliang Chen, Xiaolong Zhu, Nan Jiang, Ximing Li, Zhigang Guo

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Evidence-based complementary and alternative medicine : eCAM, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Yunpeng BaiChest Hospital, Tianjin University, Tianjin 300222, China.
Qingliang ChenChest Hospital, Tianjin University, Tianjin 300222, China.
Xiaolong ZhuTianjin Chest Hospital, Tianjin Medical University, Tianjin 300222, China.
Nan JiangChest Hospital, Tianjin University, Tianjin 300222, China.
Ximing LiChest Hospital, Tianjin University, Tianjin 300222, China.ORCID https://orcid.org/0000-0001-9275-2899
Zhigang GuoChest Hospital, Tianjin University, Tianjin 300222, China.ORCID https://orcid.org/0000-0003-3315-1596
Tianjin University · CNTianjin Chest Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThe patency and quality of transplanted great saphenous vein (GSV) can seriously influence the physical state and life quality of patients who accepted the coronary artery bypass grafting (CABG). Quercetin is known for antioxidant, antithrombotic, anti-inflammatory, and antitumor properties. In this study, we examined the protection of quercetin to the great saphenous vein from oxidative and inflammatory damage.

methodsThe GSVs were collected from 15 patients undergoing CABG and cultured. Treated the veins by H

resultsPretreatment by quercetin reduced the production of NO and MDA induced by H

conclusionThese results demonstrated that quercetin protects GSVs by reducing the oxidative damage and inflammatory response and also suppresses the abnormal thickening of venous endothelium by inhibiting cell proliferation. It reminded that, to some extent, quercetin has the potential to release the great saphenous vein graft damage.

Identifiers

PMID35003306
PMCPMC8741364
OpenAlexW4205347867

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.