ArticleEvidence-based complementary and alternative medicine : eCAM2021
Huanglian Jiedu Decoction Exerts Antipyretic Effect by Inhibiting MAPK Signaling Pathway.
Article in Evidence-based complementary and alternative medicine : eCAM, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
6 citing papers in PubMed, 46 citations in OpenAlex.
- Article
- Antipyretic Mechanism of Bai Hu Tang on LPS-Induced Fever in Rat: A Network Pharmacology and Metabolomics Analysis.Pharmaceuticals (Basel, Switzerland) · 2025Article
- Elucidation of the antipyretic and anti-inflammatory effect of 8-Frontiers in pharmacology · 2025Article
- The anti-cholestatic effects ofFrontiers in pharmacology · 2024Article
- Research Progress on the Correlation Between Hypertension and Gut Microbiota.Journal of multidisciplinary healthcare · 2024Review
- COVID-19: A Possible Contribution of the MAPK Pathway.Biomedicines · 2023Article
Corrections and comments
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Authors and funding
12 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimThe aim of this study was to explore the antipyretic effect and potential mechanism of Huanglian Jiedu Decoction (HLJDD) on LPS-induced fever in rats. MATERIALS AND
methodsThe fever rat model was established by LPS. Anal temperature of rats was measured every 1 hour after modeling. TNF-
resultsThe results showed that HLJDD can alleviate LPS-induced fever in rats. The expression levels of TNF-
conclusionThe findings suggest that HLJDD has a good antipyretic effect on LPS-induced fever in rats, which may be closely related to the inhibition of MAPK signaling pathway.
Identifiers
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.