Evidence map›Paper›PMID 35003267›Full record

ArticleCase reports in medicine2021

Physiological Stimulation of the Synthesis of Preelastic Fibers in the Dermis of a Patient with Fibrosis.

Jose Maria Pereira de Godoy, Lívia Maria Pereira de Godoy, Maria de Fatima Guerreiro Godoy, Dalisio de Santi Neto

Open access · goldAbstract readCase Reports
In one paragraph

Article in Case reports in medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.8field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 10 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Jose Maria Pereira de GodoyAdjunct Cardiology and Cardiovascular Surgery Department of the Medicine School, São José Do Rio Preto (FAMERP), CNPq (National Council for Research and Development), São Paulo, Brazil.ORCID https://orcid.org/0000-0001-5424-7787
Lívia Maria Pereira de GodoyDermatology, Instituto Lauro de Souza Lima-Bauru-Brazil, Member of Researcher Group, Clínica Godoy, São Paulo, Brazil.ORCID https://orcid.org/0000-0002-1036-8779
Maria de Fatima Guerreiro GodoyMedicine School, São José Do Rio Preto (FAMERP) and Research Group, The Clínica Godoy, São Paulo, Brazil.ORCID https://orcid.org/0000-0003-3725-7961
Dalisio de Santi NetoHospital de Base- Medicine School, São José Do Rio Preto (FAMERP), São Paulo, Brazil.ORCID https://orcid.org/0000-0002-1218-6717
Faculdade de Medicina de São José do Rio Preto · BRInstituto Lauro de Souza Lima · BRNational Council for Scientific and Technological Development · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThe aim of the present study was to report the physiological stimulation of the synthesis of preelastic fibers in the dermis of a patient with fibrosis.

designA clinical study was conducted involving the analysis of histological changes in preelastic fibers following treatment for stage II primary lymphedema for the clinical reversal of lymphedema and fibrosis.

resultsA visible, significant difference in the percentage of preelastic fibers was found between the preintervention and postintervention slides, which were confirmed by the microscopic evaluation and quantification (4.95 ± 0.64% and 14.70 ± 1.06%, respectively).

conclusionThe physiological stimulation of the lymphatic system using a specific method resulted in the clinical reduction of fibrosis, the return of the elasticity of the skin, and the stimulation of the synthesis of preelastic fibers.

Identifiers

PMID35003267
PMCPMC8739906
OpenAlexW4205700731

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.