Evidence map›Paper›PMID 35003217›Full record

ArticleFrontiers in genetics2021

Circular RNA, microRNA and Protein Profiles of the Longissimus Dorsi of Germany ZIKA and Sichuan White Rabbits.

Xiangyu Zhang, Cuixia Zhang, Chao Yang, Liangde Kuang, Jie Zheng, Li Tang, Min Lei, Congyan Li, Yongjun Ren, Zhiqiang Guo and 5 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in genetics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.2field-weighted citation impact, top 50% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 2 institutions in 1 country.

Xiangyu ZhangSichuan Animal Sciences Academy, Chengdu, China.
Cuixia ZhangSichuan Animal Sciences Academy, Chengdu, China.
Chao YangSichuan Animal Sciences Academy, Chengdu, China.
Liangde KuangSichuan Animal Sciences Academy, Chengdu, China.
Jie ZhengSichuan Animal Sciences Academy, Chengdu, China.
Li TangSichuan Animal Sciences Academy, Chengdu, China.
Min LeiSichuan Animal Sciences Academy, Chengdu, China.
Congyan LiSichuan Animal Sciences Academy, Chengdu, China.
Yongjun RenSichuan Animal Sciences Academy, Chengdu, China.
Zhiqiang GuoSichuan Animal Sciences Academy, Chengdu, China.
Yang JiSichuan Animal Sciences Academy, Chengdu, China.
Xiaodong DengSichuan Animal Sciences Academy, Chengdu, China.
Dengping HuangSichuan Animal Sciences Academy, Chengdu, China.
Gaofu WangChongqing Academy of Animal Sciences, Chongqing, China.
Xiaohong XieSichuan Animal Sciences Academy, Chengdu, China.
Sichuan Animal Science Academy · CNChongqing Academy of Animal Science · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Due to the dietetic properties and remarkable nutritive value of rabbit meat, its industry is increasing rapidly. However, the association between circular RNAs, microRNAs, and proteins and muscle fiber type, and meat quality of rabbit is still unknown. Here, using deep sequencing and iTRAQ proteomics technologies we first identified 3159 circRNAs, 356 miRNAs, and 755 proteins in the longissimus dorsi tissues from Sichuan white (SCWrabs) and Germany great line ZIKA rabbits (ZIKArabs). Next, we identified 267 circRNAs, 3 miRNAs, and 29 proteins differentially expressed in the muscle tissues of SCWrabs and ZIKArabs. Interaction network analysis revealed some key regulation relationships between noncoding RNAs and proteins that might be associated with the muscle fiber type and meat quality of rabbit. Further, miRNA isoforms and gene variants identified in SCWrabs and ZIKArabs revealed some pathways and biological processes related to the muscle development. This is the first study of noncoding RNA and protein profiles for the two rabbit breeds. It provides a valuable resource for future studies in rabbits and will improve our understanding of the molecular regulation mechanisms in the muscle development of livestock. More importantly, the output of our study will benefit the researchers and producers in the rabbit breeding program.

Indexed as

circular RNAlongissimus dorsimiRNAmusclerabbit

Identifiers

PMID35003217
PMCPMC8740122
OpenAlexW4200144787

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.