Evidence map›Paper›PMID 35003181›Full record

ReviewFrontiers in plant science2021

Mitigation of Environmental Stress-Impacts in Plants: Role of Sole and Combinatory Exogenous Application of Glutathione.

Yi Sze Koh, See Kiat Wong, Nor Hadiani Ismail, Gokhan Zengin, Acharaporn Duangjai, Surasak Saokaew, Pochamana Phisalprapa, Khang Wei Tan, Bey Hing Goh, Siah Ying Tang

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in plant science, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
5.3field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 54 citations in OpenAlex.

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  6. Review
  7. Temporal Dynamics of Gene Expression and Metabolic Rewiring in Wild Barley (International journal of molecular sciences · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 6 institutions in 4 countries.

Yi Sze KohChemical Engineering Discipline, School of Engineering, Monash University Malaysia, Subang Jaya, Malaysia.
See Kiat WongChemical Engineering Discipline, School of Engineering, Monash University Malaysia, Subang Jaya, Malaysia.
Nor Hadiani IsmailFaculty of Applied Sciences, Universiti Teknologi MARA (UiTM), Shah Alam, Malaysia.
Gokhan ZenginDepartment of Biology, Science Faculty, Selcuk University, Konya, Turkey.
Acharaporn DuangjaiUnit of Excellence in Research and Product Development of Coffee, Division of Physiology, School of Medical Sciences, University of Phayao, Mae Ka, Thailand.
Surasak SaokaewUnit of Excellence in Research and Product Development of Coffee, Division of Physiology, School of Medical Sciences, University of Phayao, Mae Ka, Thailand.
Pochamana PhisalprapaDepartment of Medicine, Division of Ambulatory Medicine, Faculty of Medicine Siriraj Hospital, Mahidol University, Salaya, Thailand.
Khang Wei TanSchool of Energy and Chemical Engineering, Xiamen University Malaysia, Sepang, Malaysia.
Bey Hing GohBiofunctional Molecule Exploratory Research Group, School of Pharmacy, Monash University Malaysia, Subang Jaya, Malaysia.
Siah Ying TangChemical Engineering Discipline, School of Engineering, Monash University Malaysia, Subang Jaya, Malaysia.
Monash University Malaysia · MYUniversity of Phayao · THSelçuk University · TRSiriraj Hospital · THUniversiti Teknologi MARA · MYXiamen University Malaysia · MY

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Glutathione (GSH; γ-glutamyl-cysteinyl-glycine), a low-molecular-weight thiol, is the most pivotal metabolite involved in the antioxidative defense system of plants. The modulation of GSH on the plant in response to environmental stresses could be illustrated through key pathways such as reactive oxygen species (ROS) scavenging and signaling, methylglyoxal (MG) detoxification and signaling, upregulation of gene expression for antioxidant enzymes, and metal chelation and xenobiotic detoxification. However, under extreme stresses, the biosynthesis of GSH may get inhibited, causing an excess accumulation of ROS that induces oxidative damage on plants. Hence, this gives rise to the idea of exploring the use of exogenous GSH in mitigating various abiotic stresses. Extensive studies conducted borne positive results in plant growth with the integration of exogenous GSH. The same is being observed in terms of crop yield index and correlated intrinsic properties. Though, the improvement in plant growth and yield contributed by exogenous GSH is limited and subjected to the glutathione pool [GSH/GSSG; the ratio of reduced glutathione (GSH) to oxidized glutathione (GSSG)] homeostasis. Therefore, recent studies focused on the sequenced application of GSH was performed in order to complement the existing limitation. Along with various innovative approaches in combinatory use with different bioactive compounds (proline, citric acid, ascorbic acid, melatonin), biostimulants (putrescine,

Indexed as

biostimulantcyanobacteriaenvironmental stressesglutathioneplant metabolite

Identifiers

PMID35003181
PMCPMC8728365
OpenAlexW4200206603

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.